Box-Behnken Design and Molecular Docking Assisted Quenching Spectrofluorimetric Method for the Quantitation of Citalopram HBr in Commercial Dosage Forms.

Syed Najmul Hejaz Azmi, Wafa Aqib Nasir Al Rawahi, Zamzam Sulaiman Zahran Al Nabhani, Al Anood Ahmed Abdullah Al Farsi, Qamar Uddin Ahmed, Mahboob Alam, Md Abdur Rashid Mia, Nafisur Rahman

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Article in Journal of fluorescence, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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8 authors.

Syed Najmul Hejaz AzmiApplied Sciences Department, College of Applied Sciences and Pharmacy, University of Technology and Applied Sciences-Muscat, Al Khuwair 133, P. O. Box 74, Muscat, Sultanate of Oman. syed.najmul@utas.edu.om.

Wafa Aqib Nasir Al RawahiApplied Sciences Department, College of Applied Sciences and Pharmacy, University of Technology and Applied Sciences-Muscat, Al Khuwair 133, P. O. Box 74, Muscat, Sultanate of Oman.

Zamzam Sulaiman Zahran Al NabhaniApplied Sciences Department, College of Applied Sciences and Pharmacy, University of Technology and Applied Sciences-Muscat, Al Khuwair 133, P. O. Box 74, Muscat, Sultanate of Oman.

Al Anood Ahmed Abdullah Al FarsiApplied Sciences Department, College of Applied Sciences and Pharmacy, University of Technology and Applied Sciences-Muscat, Al Khuwair 133, P. O. Box 74, Muscat, Sultanate of Oman.

Qamar Uddin AhmedDrug Discovery and Synthetic Chemistry Research Group, Department of Pharmaceutical Chemistry, Kulliyyah of Pharmacy, International Islamic University Malaysia, Pahang Darul Makmur, Kuantan, 25200, Malaysia.

Mahboob AlamDivision of Smart Safety Engineering, Dongguk University Wise, 123 Dongdae-ro, Gyeongju-si, 780714, Republic of Korea.

Md Abdur Rashid MiaCooperative Research, Extension, and Education Services (CREES), Northern Marianas College, P.O. Box 501250, Saipan, MP, 96950, USA.

Nafisur RahmanDepartment of Chemistry, Aligarh Muslim University, Aligarh, Uttar Pradesh, 202002, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A simple, sensitive and accurate spectrofluorimetric method was presented for the determination of citalopram hydrobromide (CTM) in tablets. The method was based on the quenching of bovine serum albumin (BSA) fluorescence with CTM at pH 7.4. The fluorescence intensities were measured at 342 nm after excitation at 279 nm. Various factors affecting the quenching of BSA fluorescence were optimized by response surface methodology (RSM) through Box-Behnken design (BBD. The plot of F

Indexed as

CitalopramMolecular Docking SimulationAnimalsCattleLimit of DetectionSerum Albumin, BovineSpectrometry, FluorescenceTabletsCitalopramSerum Albumin, BovineTabletsBox-Behnken designCitalopram HBrComplexMoGAPIMolecular dockingQuenching

Identifiers

PMID39964649

DOI10.1016/j.greeac.2024.100126

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.