Evidence map›Paper›PMID 39964546›Full record

Trial reportEuropean journal of nutrition2025

Dietary climate impact correlates ambiguously with health biomarkers- a randomised controlled trial in healthy Finnish adults.

Merja Saarinen, Tiina Pellinen, Joel Kostensalo, Jouni Nousiainen, Katri Joensuu, Suvi T Itkonen, Anne-Maria Pajari

Registry-linked trialAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in European journal of nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03206827 (Effects of Dietary Plant and Animal Proteins on Biomarkers of Colorectal Cancer and Type 2 Diabetes in Healthy Adults), which is not on this map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03206827 nacompletednot on this map

Effects of Dietary Plant and Animal Proteins on Biomarkers of Colorectal Cancer and Type 2 Diabetes in Healthy Adults

TypeinterventionalSponsorUniversity of HelsinkiRan2016 to 2021Enrolled147ConditionsColorectal Cancer, Type2 DiabetesArms70% animal, 30% plant proteins in diet, 50% animal, 50% plant proteins in diet, 30% animal, 70% plant proteins in diet
3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Merja SaarinenNatural Resources Institute Finland (Luke), Tietotie 4, Jokioinen, FI-31600, Finland. merja.saarinen@luke.fi.ORCID http://orcid.org/0000-0002-4375-7682
Tiina PellinenDepartment of Food and Nutrition, P.O. Box 66, University of Helsinki, FI-00014, Finland.ORCID http://orcid.org/0000-0002-2583-4496
Joel KostensaloNatural Resources Institute Finland (Luke), Yliopistokatu 6B, Joensuu, FI-80100, Finland.ORCID http://orcid.org/0000-0001-9883-1256
Jouni NousiainenNatural Resources Institute Finland (Luke), Tietotie 4, Jokioinen, FI-31600, Finland.ORCID http://orcid.org/0000-0002-5583-4665
Katri JoensuuNatural Resources Institute Finland (Luke), Latokartanonkaari 9, Helsinki, FI FI-00790, Finland.ORCID http://orcid.org/0000-0002-5698-1309
Suvi T ItkonenDepartment of Food and Nutrition, P.O. Box 66, University of Helsinki, FI-00014, Finland.ORCID http://orcid.org/0000-0003-1635-8229
Anne-Maria PajariDepartment of Food and Nutrition, P.O. Box 66, University of Helsinki, FI-00014, Finland.ORCID http://orcid.org/0000-0002-6248-4560

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeA transition to more plant-rich diets is an effective way to reduce the climate impact of a diet. Using a whole-diet approach, we studied how partial replacement of animal-sourced with plant-sourced proteins affected the dietary climate impact while simultaneously considering diet-related health biomarkers.

methodsIn a 12-week randomised controlled trial, 107 women and 29 men were assigned into three diet groups (ANIMAL, 50/50, PLANT) with animal-to-plant-protein ratios of 70/30, 50/50, and 30/70, respectively. Life-cycle-assessment-based coefficients for foods were used to assess the climate impact of the diet groups, based on four-day food records. Correlations between climate impact and biomarkers were assessed.

resultsThe climate impact (CO

conclusionReplacing animal-sourced proteins with plant-sourced proteins reduced the climate impact of the diet. The relationship between climate impact and biomarkers was more ambiguous indicated by both beneficial and harmful indicators within lower climate impacts. CLINICAL TRIAL REGISTRY: NCT03206827; registration date: 2017-06-30.

Indexed as

BiomarkersClimateDietAdultAnimal Proteins, DietaryDietary ProteinsDiet RecordsFemaleFinlandHumansMaleMiddle AgedAnimal Proteins, DietaryBiomarkersDietary ProteinsAnimal proteinClimate impactDietary changeFood transitionPlant proteinSustainable diet

Identifiers

PMID39964546
PMCPMC11836174

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.