Evidence map›Paper›PMID 39964515›Full record

ReviewPathologie (Heidelberg, Germany)2025

[Exanthematic drug eruption].

Mirjana Ziemer, Elisabeth Livingstone

Abstract readEnglish AbstractReview
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In one paragraph

Review in Pathologie (Heidelberg, Germany), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Mirjana ZiemerKlinik für Dermatologie, Venerologie und Allergologie, Universitätsmedizin Leipzig, Philipp-Rosenthal-Str. 23, 04103, Leipzig, Deutschland. mirjana.ziemer@medizin.uni-leipzig.de.ORCID http://orcid.org/0000-0001-6488-1917
Elisabeth LivingstoneKlinik für Dermatologie, Allergologie und Venerologie, Universitätsmedizin Essen, Essen, Deutschland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBesides reactions of the IgE-mediated immediate type, medicamentous therapies can cause a variety of different mucocutaneous adverse events. Exanthematous manifestations require a fast and certain diagnosis due to their extent, sometimes rapid progression, and mucous membrane or organ involvement.

objectivesThe spectrum of non-IgE-mediated exanthematic drug reactions is covered. MATERIAL AND

methodsThe most relevant reactions are portrayed clinically and histopathologically.

resultsDisplayed are classical maculo-papular drug eruption, lichenoid drug reaction, acute generalized exanthematic pustulosis (AGEP), severe potentially life-threatening drug reactions such as Stevens-Johnson syndrome (SJS), and toxic epidermal necrolysis (TEN) as well as generalized bullous fixed drug eruption (GBFDE), drug reaction with eosinophilia and systemic symptoms (DRESS), and some others.

conclusionsCutaneous drug-related side effects cover a broad spectrum. Important for the correct treatment is a reliable diagnosis. In the case of severe, life-threatening drug reactions, however, permanent discontinuation of the drug is essential.

Indexed as

Drug EruptionsExanthemaAcute Generalized Exanthematous PustulosisDiagnosis, DifferentialDrug Hypersensitivity SyndromeHumansLichenoid EruptionsSkinStevens-Johnson SyndromeAcute generalized exanthematic pustulosisDrug reaction with eosinophilia and systemic symptomsGeneralized bullous fixed drug eruptionLichenoid drug reactionStevens-Johnson syndromeToxic epidermal necrolysis

Identifiers

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.