ArticleQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2025
The effects of stigma and social support on the health-related quality of life of people with drug resistance tuberculosis in Lagos, Nigeria.
Article in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- Article
- Tuberculosis- and Diabetes Mellitus-Associated Knowledge, Stigma, and Health-Seeking Behaviour in Ghana.International journal of environmental research and public health · 2026Article
- Tuberculosis-related stigma and associated factors among people with pulmonary tuberculosis predominantly co-infected with HIV in Kampala, Uganda: a cross-sectional study.Journal of clinical tuberculosis and other mycobacterial diseases · 2026Article
- Predictive Analysis of Drug-Resistant Tuberculosis: Integrating Molecular Markers, Clinical Governance, and Community-Engaged Education in Rural South Africa.Diseases (Basel, Switzerland) · 2026Article
- Settings, characteristics, and experiences of stigma among people with tuberculosis in Kenya: National survey results.PLOS global public health · 2026Article
- Perceived stigma among hospitalized pulmonary tuberculosis patients in Hue Central Hospital: A 2024 mixed method study in Vietnam.PLOS global public health · 2026Article
- Psychosocial Adaptation After Heart Transplantation: The Chain-Mediating Effect of Self-Esteem and Death Anxiety on Social Support and Quality of Life in China.Behavioral sciences (Basel, Switzerland) · 2025Article
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Abstract
purposeThis study assessed the effects of TB stigma and social support on the health-related quality of life (HRQoL) of people living with drug-resistant tuberculosis (DR-TB) in Lagos, Nigeria.
methodsA cross-sectional study was conducted in five DR-TB treatment centres in Lagos, Nigeria, between September and December 2023. A total of 203 adults on DR-TB treatment were recruited to complete a questionnaire including the Redwood DR-TB stigma scale, the Functional Assessment of Chronic Illness Therapy-TB (FACCIT) scale, and the Multidimensional Scale of Perceived Social Support (MSPSS). Student 't' test/one-way ANOVA, Pearson's correlation, and hierarchical linear regression analysis were conducted to explore the factors associated with HRQoL and the relationships between stigma, social support, and HRQoL.
resultsThe mean overall HRQoL was 41.1 ± 12.9 among people with DR-TB. The HRQoL score of the physical domain was the lowest (25.8 ± 13.8). Participants who were young, male, single, with higher education, and HIV-negative had higher HRQoL than their counterparts (p < 0.05). Stigma was negatively associated with HRQoL, while social support was positively related, collectively explaining 57.6% of the variance. In the final model, social support contributed more (B = 0.576) to predicting HRQoL than did stigma (B = - 0.414).
conclusionThe overall HRQoL of people with DR-TB in Lagos, Nigeria, was poor. Strategies that improve social support systems and reduce stigma are needed to improve this. Further studies are also required to assess the changes in HRQoL over time and evaluate the impact of specific stigma-reduction interventions.
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