Evidence map›Paper›PMID 39964230›Full record

ArticleThe journal of spinal cord medicine2026

Indications, feasibility safety and efficacy of dorsal rhizotomy at the level of the conus medullaris (conus deafferentation) in individuals with spinal cord injury.

Ines Kurze, Elena Jakisch, Martin Jakisch, Frank Werner, Birgitt Kowald, Klaus Golka, Ralf Böthig

Abstract read
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Article in The journal of spinal cord medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Ines KurzeDepartment of Paraplegiology and Neuro-Urology, Centre for Spinal Cord Injuries, Zentralklinik Bad Berka, Bad Berka, Germany.
Elena JakischDepartment of Neuro-Urology, Centre for Spinal Cord Injuries, BG Klinikum Hamburg, Hamburg, Germany.
Martin JakischDepartment of Neurosurgery, BG Klinikum Hamburg, Hamburg, Germany.
Frank WernerDepartment of Neurosurgery, Zentralklinik Bad Berka, Bad Berka, Germany.
Birgitt KowaldCentre for Clinical Research, BG Klinikum Hamburg, Hamburg, Germany.
Klaus GolkaLeibniz Research Centre for Working Environment and Human Factors at TU Dortmund (IfADo), Dortmund, Germany.
Ralf BöthigDepartment of Neuro-Urology, Centre for Spinal Cord Injuries, BG Klinikum Hamburg, Hamburg, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

STUDY

designRetrospective non-controlled intervention study.

objectivesTo assess indications, feasibility, safety and efficacy of dorsal rhizotomy at the level of conus medullaris (conus deafferentation - CDAF) in individuals with spinal cord injury/disease (SCI/D).

settingTwo specialized tertiary German centers for spinal cord injuries.

methodsIn addition to a detailed description of the surgical procedure (including two technical variants: hemilaminectomy and osteoplastic laminotomy), an analysis of the surgical reports on intra- and postoperative complications and an evaluation of the pre- and postoperative paraplegiologic and neuro-urologic parameters of SCI/D patients with CDAF are presented.

resultsA total of 30 patients, 6 of them women, 22 with complete, 8 with incomplete SCI/D underwent CDAF. The most common indications were therapy-refractory detrusor overactivity, spasticity of the lower limbs and autonomic dysreflexia, usually with several simultaneous indications.Except for one antibiotic-treated wound infection, no severe CDAF-associated complications were documented. Urodynamic parameters (maximum detrusor pressure, maximum cystometric capacity) improved significantly (

conclusionsThe present study identified different indications for the use of CDAF that can be performed safely and efficiently with very few intraoperative and postoperative complications. We see a high potential in this method for the improvement of the paraplegiological and neuro-urological therapy spectrum.

Indexed as

RhizotomySpinal Cord InjuriesAdultAgedFeasibility StudiesFemaleHumansMaleMiddle AgedRetrospective StudiesTreatment OutcomeYoung Adultautonomic dysreflexiaConus deafferentationdorsal rhizotomyneurogenic lower urinary tract dysfunction (NLUTD)sacral deafferentation

Identifiers

PMID39964230
PMCPMC12781942

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.