Evidence map›Paper›PMID 39964154›Full record

ArticleInfection and immunity2025

Establishment and characterization of persistent

Safaa Bouheraoua, Sven Cleeves, Matthias Preusse, Mathias Müsken, Peter Braubach, Maximilian Fuchs, Christine Falk, Katherina Sewald, Susanne Häussler

Abstract read
In one paragraph

Article in Infection and immunity, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Bridging bench and bedside: translational omics ofEuropean respiratory review : an official journal of the European Respiratory Society · 2026
    Review
  2. HDAC6 inhibition reducesInfection and immunity · 2026
    Article
  3. Modeling chronic infection withInfection and immunity · 2026
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Safaa BouheraouaInstitute for Molecular Bacteriology, TWINCORE, Centre for Experimental and Clinical Infection Research, Hannover, Germany.ORCID 0009-0002-8237-5094
Sven CleevesFraunhofer Institute for Toxicology and Experimental Medicine, Hannover, Germany.
Matthias PreusseDepartment of Molecular Bacteriology, Helmholtz Center for Infection Research, Braunschweig, Germany.
Mathias MüskenCentral Facility for Microscopy, Helmholtz Center for Infection Research, Braunschweig, Germany.ORCID 0000-0002-5624-1378
Peter BraubachInstitute for Pathology, Hannover Medical School, Hannover, Germany.
Maximilian FuchsFraunhofer Institute for Toxicology and Experimental Medicine, Hannover, Germany.
Christine FalkInstitute for Transplantation Immunology, Hannover Medical School, Hannover, Germany.
Katherina Sewald *Fraunhofer Institute for Toxicology and Experimental Medicine, Hannover, Germany.
Susanne Häussler *Institute for Molecular Bacteriology, TWINCORE, Centre for Experimental and Clinical Infection Research, Hannover, Germany.ORCID 0000-0001-6141-9102

Funding

Deutsche Forschungsgemeinschaft (DFG) EXC 2155 RESIST - Project ID 390874280, SFB/TRR-298-SIIRI - Project-ID 426335750, SPP 2389 (HA 3299/9-1 AOBJ 687646)Deutscher Akademischer Austauschdienst (DAAD) Graduate School Scholarship Program (GSSP)EC | European Research Council (ERC) Consolidator Grant COMBAT 724290Ministry of Science and Culture of Lower Saxony (Niedersächsisches Ministerium für Wissenschaft und Kultur) BacData ZN3428Novo Nordisk Foundation NNF 18OC0033946
6 · The paper itself

Abstract

Bacteria exhibit distinct behaviors in laboratory settings compared to infection environments. The presence of host cells induces changes in bacterial activity, while pathogens trigger immune responses that shape the microenvironment. Studying infection dynamics by microscopy, cytokine screening, and dual RNA sequencing in an air-liquid interface model, we found that prolonged

Indexed as

Epithelial CellsPersistent InfectionPseudomonas aeruginosaPseudomonas InfectionsRespiratory MucosaBiofilmsHost-Pathogen InteractionsHumansVirulence3D in vitro modelsairway infection modelbacterial infectionhost–pathogen interactionslung infectionpersistent infectionsPseudomonas aeruginosa

Identifiers

PMID39964154
PMCPMC11895474

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.