Evidence map›Paper›PMID 39964058›Full record

ArticleJournal of agricultural and food chemistry2025

Novel UHPLC-(+ESI)MS/MS Method for Determining Amygdalin, Prunasin and Total Cyanide in Almond Kernels and Hulls (

Elyse Doria, Larry Lerno, Mary-Ann Chen, Jihyun Lee, Guangwei Huang, Alyson E Mitchell

Abstract readEvaluation Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of agricultural and food chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Elyse DoriaDepartment of Food Science and Technology, University of California Davis, One Shields Avenue, Davis, California 95616, United States.
Larry LernoDepartment of Viticulture and Enology, University of California Davis, One Shields Avenue, Davis, California 95616, United States.ORCID 0000-0001-5292-3358
Mary-Ann ChenDepartment of Food Science and Technology, University of California Davis, One Shields Avenue, Davis, California 95616, United States.
Jihyun LeeDepartment of Food and Nutrition, Seoul National University, Seoul 08826, Republic of Korea.
Guangwei HuangAlmond Board of California, Suite 1500, 1150 Ninth Street, Modesto, California 95354, United States.
Alyson E MitchellDepartment of Food Science and Technology, University of California Davis, One Shields Avenue, Davis, California 95616, United States.ORCID 0000-0003-0286-5238

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Almonds contain cyanogenic glycosides (CNGs), prunasin and amygdalin, which generate hydrogen cyanide upon hydrolysis. Different extraction and analytical methods are currently used to measure CNGs or cyanide (CN), necessitating distinct samples and can lead to inconsistent or incomparable results. To address this, we describe a method that uses ultrasonic-assisted sample extraction. Amygdalin and prunasin are measured directly in the extract, whereas CN is measured in the extract after derivatization with cysteine ethyl ester to form a cyano-

Indexed as

AmygdalinCyanidesGlycosidesPlant ExtractsPrunus dulcisTandem Mass SpectrometryChromatography, High Pressure LiquidNitrilesSeedsAmygdalinCyanidescyanogenic glycosidesGlycosidesNitrilesPlant Extractsprunasincyanogenesiscyanogenic glycosidescysteine ethyl esterderivatizationUHPLC-(+ESI)QTOF-MS/MS

Identifiers

PMID39964058
PMCPMC11887422

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.