Evidence map›Paper›PMID 39963803›Full record

ArticleNanomedicine (London, England)2025

Polyol-modified deformable liposomes fortified contact lenses for improved ocular permeability.

Jeel Dave, Harshilkumar Jani, Yashkumar Patel, Popat Mohite, Abhijeet Puri, Vijay R Chidrawar, Deepanjan Datta, Sony Priyanka Bandi, Ketan Ranch, Sudarshan Singh

Abstract read
In one paragraph

Article in Nanomedicine (London, England), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Jeel DaveDepartment of Pharmaceutics and Pharmaceutical Technology, L. M. College of Pharmacy, Ahmedabad, India.
Harshilkumar JaniDepartment of Pharmaceutics and Pharmaceutical Technology, L. M. College of Pharmacy, Ahmedabad, India.
Yashkumar PatelDepartment of Pharmaceutics and Pharmaceutical Technology, L. M. College of Pharmacy, Ahmedabad, India.
Popat MohiteAETs St. John Institute of Pharmacy and Research, Palghar, India.
Abhijeet PuriAETs St. John Institute of Pharmacy and Research, Palghar, India.
Vijay R ChidrawarSchool of Pharmacy and Technology Management, SVKM's Narsee Monjee Institute of Management Studies (NMIMS), Deemed-to-University, Green Industrial Park, Hyderabad, India.
Deepanjan DattaDepartment of Pharmaceutics, Manipal College of Pharmaceutical Sciences, Manipal Academy of Higher Education, Manipal, India.
Sony Priyanka BandiDepartment of Pharmacy, Birla Institute of Technology and Science (BITS) Pilani, Hyderabad, India.
Ketan RanchDepartment of Pharmaceutics and Pharmaceutical Technology, L. M. College of Pharmacy, Ahmedabad, India.
Sudarshan SinghOffice of Research Administration, Chiang Mai University, Chiang Mai, Thailand.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo develop a glycerol modified liposomes to effectively deliver active agents into posterior segment of the eye for the management of posterior uveitis. MATERIALS AND

methodsThe modified liposome enhanced with glycerol as an edge activator was fabricated using a 3 RESULTS AND

conclusionsNano-vesicles resulted in size and deformability index of 200.5 ± 15 nm and 11.58, respectively, with entrapment efficiency of 80.98% of the drug. Moreover, the optimized lenses demonstrated 71%) of swelling and transmittance of 87%). In addition,

Indexed as

Contact LensesLiposomesPolymersAnimalsDexamethasoneDrug Delivery SystemsDrug LiberationGlycerolHumansLecithinsOphthalmic SolutionsParticle SizePermeabilityDexamethasoneGlycerolLecithinsLiposomesOphthalmic SolutionsPolymerspolyolContact lensesexperimental designglycerosomesocular drug deliverypolyol modified liposomes

Identifiers

PMID39963803
PMCPMC11970793

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.