ArticleDiabetes, obesity & metabolism2025
Global, regional and national burden of ischaemic heart disease attributable to high body mass index and low physical activity from 1990 to 2021.
Article in Diabetes, obesity & metabolism, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- National divergence in cardio-kidney-metabolic syndrome burden and implications for health policy: a global burden of disease analysis with projections to 2050.Frontiers in public health · 2026Article
- Formulation, characterization, and evaluation of transdermal patches of ranolazine for chronic angina pectoris.Naunyn-Schmiedeberg's archives of pharmacology · 2026Article
- Low physical activity-related disease burden, 1990-2021: assessment of global trends and social determinants based on GBD 2021 data.Journal of global health · 2025Article
- Kynurenine as a Predictor of Long-Term Mortality: A 10-Year Follow-Up from the KORONEF Registry.Biomedicines · 2025Article
- Global, regional and national burden of ischaemic heart disease attributable to high body mass index and low physical activity from 1990 to 2021.Diabetes, obesity & metabolism · 2025Article
- Spatial-temporal characteristics and prediction of ischemic heart disease burden in the working population aged 15 to 59 years in China.Frontiers in cardiovascular medicine · 2025Article
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8 authors.
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Abstract
aimThis study aimed to estimate the distribution of and changes in the global burden of ischaemic heart disease (IHD) attributable to high body mass index (BMI) and low physical activity (PA) from 1990 to 2021.
methodsData on deaths, disability-adjusted life years (DALYs) and age-standardized rates for IHD attributable to high BMI and low PA were extracted from the Global Burden of Disease 2021 study. Temporal trends by gender, region and Socio-Demographic Index (SDI) were analysed using joinpoint regression. Decomposition, health inequality analysis and Bayesian model were utilized.
resultsFrom 1990 to 2021, global DALYs and deaths for IHD attributable to high BMI and low PA nearly doubled, despite a decline in age-standardized DALYs ([average annual percent change (AAPC) = -0.26, 95% uncertainty interval (95% UI): -0.45, -0.07), (AAPC = -1.03, 95% UI:-1.18, -0.88]) and deaths rates ([AAPC = -0.53, 95% UI: -0.72, -0.33], [AAPC = -1.13,95% UI: -1.34, -0.92]), respectively. The burden of IHD due to high BMI was predominantly seen in males, while low PA was more prevalent in females. Significant regional and national variation was observed, with the burden shifting from high SDI regions to middle or low SDI regions. Population growth and aging have exacerbated this burden. Health inequities have shown improvement between 1990 and 2021. Projections for the next 15 years suggest rising global age-standardized DALYs and death rates of IHD attributable to high BMI, while those attributable to low PA may decrease.
conclusionsSince 1990, the global and regional impact of IHD attributable to high BMI and low PA remains significant, with disparities by gender, age, region and SDI. Countries should implement effective measures to control BMI and promote PA to reduce the IHD burden.
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