ArticleMagnetic resonance in medicine2025
Interpretation of inhomogeneous magnetization transfer in myelin water using a four-pool model with dipolar reservoirs.
Article in Magnetic resonance in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- SNR-Efficient Inhomogeneous Magnetization Transfer (ihMT) for Clinical Applications at 7 T.Magnetic resonance in medicine · 2026Article
- Dipolar Order Mapping Based on Spin-Lock Magnetic Resonance Imaging.NMR in biomedicine · 2026Article
- Reducing Inhomogeneous MT (ihMT) Acquisition Time Using Frequency Alternation at Low Duty Cycle for Single Offset (FALSO) MT Preparations.Magnetic resonance in medicine · 2026Article
- Quantitative Comparison of Multi-Echo Spin Echo and Multi-Echo Gradient Echo Myelin Water Imaging in a Panel of Mbp Enhancer-Edited Mouse Lines.Magnetic resonance in medicine · 2026Article
- Interpretation of inhomogeneous magnetization transfer in myelin water using a four-pool model with dipolar reservoirs.Magnetic resonance in medicine · 2025Article
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Authors and funding
8 authors.
Funding
Abstract
purposeTo confirm ihMT's specificity to myelin, an ihMT presaturation module was combined with a Poon-Henkelman multi-echo spin-echo readout to separate the ihMT signal in myelin water from intra-/extra-cellular water. This study explored the relationship between two quantitative myelin imaging techniques and measured the ihMT signal of myelin water.
methodsSix rats were injured; three were sacrificed three weeks post-injury, and three were sacrificed eight weeks post-injury, and three healthy control rats were also sacrificed. The nine formalin-fixed rat spinal cords were imaged using a Poon-Henkelman multi-echo spin-echo readout with an ihMT prepulse at different strengths of
resultsThe proposed model was able to characterize the ihMT decay signal in myelin water and intra-/extra-cellular water pool. From this proposed four-pool model with dipolar order reservoirs, we see a drop in the
conclusionThe drop in
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Registered trials
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