Evidence map›Paper›PMID 39963702›Full record

ArticleOpen forum infectious diseases2025

Choice of Drug for Malaria Prevention During Pregnancy Does Not Affect Infant Serologic Responses to

Amed Ouattara, Liana R Andronescu, Matthew Adams, Ankur Sharma, Rie Nakajima, Aarti Jain, Omid Taghavian, Algis Jasinskas, Philip L Felgner, Don P Mathanga and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Open forum infectious diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Amed OuattaraMalaria Research Program, Center for Vaccine Development and Global Heath, School of Medicine, University of Maryland, Baltimore, Maryland, USA.ORCID https://orcid.org/0000-0003-1964-7130
Liana R AndronescuMalaria Research Program, Center for Vaccine Development and Global Heath, School of Medicine, University of Maryland, Baltimore, Maryland, USA.
Matthew AdamsMalaria Research Program, Center for Vaccine Development and Global Heath, School of Medicine, University of Maryland, Baltimore, Maryland, USA.
Ankur SharmaMalaria Research Program, Center for Vaccine Development and Global Heath, School of Medicine, University of Maryland, Baltimore, Maryland, USA.
Rie NakajimaVaccine Research and Development Center, Department of Physiology and Biophysics, School of Medicine, University of California, Irvine, Irvine, California, USA.ORCID https://orcid.org/0000-0002-6026-3342
Aarti JainVaccine Research and Development Center, Department of Physiology and Biophysics, School of Medicine, University of California, Irvine, Irvine, California, USA.ORCID https://orcid.org/0000-0002-9536-0097
Omid TaghavianVaccine Research and Development Center, Department of Physiology and Biophysics, School of Medicine, University of California, Irvine, Irvine, California, USA.
Algis JasinskasVaccine Research and Development Center, Department of Physiology and Biophysics, School of Medicine, University of California, Irvine, Irvine, California, USA.
Philip L FelgnerVaccine Research and Development Center, Department of Physiology and Biophysics, School of Medicine, University of California, Irvine, Irvine, California, USA.
Don P MathangaMalaria Alert Center, Kamuzu University of Health Sciences, Blantyre, Malawi.
Jobiba ChinkhumbaMalaria Alert Center, Kamuzu University of Health Sciences, Blantyre, Malawi.
Miriam K LauferMalaria Research Program, Center for Vaccine Development and Global Heath, School of Medicine, University of Maryland, Baltimore, Maryland, USA.ORCID https://orcid.org/0000-0001-8300-9593
Mark A TravassosMalaria Research Program, Center for Vaccine Development and Global Heath, School of Medicine, University of Maryland, Baltimore, Maryland, USA.

Funding

Malaria variant surface antigen expression and vulnerability to disease in Malian children with Hemoglobin C traitR01HL146377 · NHLBI · UNIVERSITY OF MARYLAND BALTIMORE · PI TRAVASSOS, MARK A · 2019 to 2023
$1.9M
Mentoring in patient-oriented research in global healthK24AI114996 · NIAID · UNIVERSITY OF MARYLAND BALTIMORE · PI LAUFER, MIRIAM K. · 2016 to 2025
$1.6M
Impact of malaria during pregnancy on infant healthR21AI121990 · NIAID · UNIVERSITY OF MARYLAND BALTIMORE · PI LAUFER, MIRIAM K. · 2017 to 2018
$357k
NHLBI NIH HHS R01 HL146377NIAID NIH HHS K24 AI114996NIAID NIH HHS R21 AI121990
6 · The paper itself

Abstract

While sulfadoxine-pyrimethamine has been the primary drug in intermittent preventive treatment in pregnancy, dihydroartemisinin-piperaquine (DP) is being considered as an alternative. DP may lead to lower antimalarial antibodies in the mother, resulting in higher risk of malaria in infancy. We probed cord blood sera collected from women enrolled in a clinical trial of sulfadoxine-pyrimethamine vs DP on a protein microarray containing diverse

Indexed as

chemoprophylaxisdihydroartemisinin-piperaquineinfantspfEMP1sulfadoxine-pyrimethamine

Identifiers

PMID39963702
PMCPMC11832042

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.