Evidence map›Paper›PMID 39963584›Full record

ReviewBJUI compass2025

Comparing GreenLight PVP and HoLEP beyond 5 years: A systematic review of long-term functional outcomes and reoperation rates.

Arthur Yim, Matthew Alberto, Xingqi Yan, Damien Bolton, Lih-Ming Wong, Kapil Sethi

Abstract readReview
In one paragraph

Review in BJUI compass, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Trial
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Arthur YimDepartment of Urology Austin Health Heidelberg Victoria Australia.ORCID https://orcid.org/0000-0003-2045-1231
Matthew AlbertoDepartment of Urology Austin Health Heidelberg Victoria Australia.ORCID https://orcid.org/0000-0003-3722-7754
Xingqi YanDepartment of Surgery The University of Melbourne Melbourne Victoria Australia.ORCID https://orcid.org/0009-0002-0559-228X
Damien BoltonDepartment of Urology Austin Health Heidelberg Victoria Australia.ORCID https://orcid.org/0000-0002-5145-6783
Lih-Ming WongDepartment of Urology Austin Health Heidelberg Victoria Australia.ORCID https://orcid.org/0000-0003-0490-7876
Kapil SethiDepartment of Urology Austin Health Heidelberg Victoria Australia.ORCID https://orcid.org/0000-0002-6037-8895

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: This study aimed to compare long-term (≥ 5 years) functional outcomes and reoperation rates following holmium laser enucleation of prostate (HoLEP) vs GreenLight photoselective vaporisation of prostate (GLPVP). Methods: MEDLINE, Embase and Cochrane databases were searched from inception to December 2023. Included were randomised controlled trials (RCTs), cohort studies and case series studying HoLEP and/or GLPVP, where functional outcomes and reoperation rates were reported. Studies with <5-year follow-up were excluded. Evidence was synthesised as a comparison across all parameters. Quality of evidence was assessed with the Newcastle-Ottawa Scale. Results: Of 3047 records identified, 25 were eligible, including two RCTs, two cohort studies, one cross-sectional study and 20 case series. Twenty-three studies focused on HoLEP or GLPVP, whilst two were comparative studies. HoLEP demonstrated long-term durability of outcomes and low reoperation rates (mean 4.1%, range 2.0%-6.3%) at a mean follow-up of 7.3 years. GLPVP also had durable outcomes at 5-year follow-up, but inconclusive evidence for improvements at 10 years. Reoperation rates were also higher (mean 12.6%, range 3.8%-33.3%). This is in keeping with findings of comparative studies, where HoLEP demonstrated greater improvements in all functional parameters except PVR, and lower reoperation rates. Findings are limited by patient attrition, lack of comparative studies and long-term data beyond 10 years. Three studies examined the 180-W GLPVP model at 5 years showed superior durability to earlier 80-W/120-W models. Conclusions: Current evidence suggests that HoLEP provides significantly greater functional improvements and a lower reoperation rate when compared with the GLPVP 80-W/120-W model at 5-year follow-up. The 180-W model is comparable with HoLEP based on limited data at 5 years, but there is a lack of data beyond 10 years for longer-term functional outcomes.

Indexed as

benign prostatic hyperplasiadurabilityfunctional outcomesGreenLight photoselective vaporisation of prostateholmium laser enucleation of prostatereoperation

Identifiers

PMID39963584
PMCPMC11832299

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.