Evidence map›Paper›PMID 39963554›Full record

ArticleBiochemistry research international2025

Potential Mechanisms of Lactate Dehydrogenase and Bovine Serum Albumin Proteins as Antioxidants: A Mixed Experimental-Computational Study.

Jing Ye, Amy Bounds, Madeline Crumpton, Mallory Long, Haley McDonough, Isabella Srikhirisawan, Shanzhen Gao

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biochemistry research international, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jing YeDepartment of Chemistry and Biochemistry, Salem College, Winston-Salem, North Carolina, USA.ORCID https://orcid.org/0000-0002-5146-7837
Amy BoundsDepartment of Chemistry and Biochemistry, Salem College, Winston-Salem, North Carolina, USA.ORCID https://orcid.org/0000-0002-5519-045X
Madeline CrumptonDepartment of Chemistry and Biochemistry, Salem College, Winston-Salem, North Carolina, USA.ORCID https://orcid.org/0009-0002-8995-2659
Mallory LongDepartment of Chemistry and Biochemistry, Salem College, Winston-Salem, North Carolina, USA.
Haley McDonoughDepartment of Chemistry and Biochemistry, Salem College, Winston-Salem, North Carolina, USA.ORCID https://orcid.org/0000-0002-8890-7584
Isabella SrikhirisawanDepartment of Chemistry and Biochemistry, Salem College, Winston-Salem, North Carolina, USA.ORCID https://orcid.org/0000-0002-0269-8065
Shanzhen GaoDepartment of Computer Information Systems, Virginia State University, Petersburg, Virginia, USA.ORCID https://orcid.org/0000-0002-3856-2530

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Proteins have shown varying degrees of antioxidant activity. This study examined the potential mechanisms of interactions between proteins and radicals using chemical kinetics and computational methods. The study quantified the antioxidant activity of lactate dehydrogenase (LDH) and bovine serum albumin (BSA) through Trolox equivalent antioxidant capacity (TEAC) and oxygen radical absorbance capacity (ORAC) assays. BSA was about seven times and LDH 12 times more potent as antioxidants for 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonate) (ABTS

Identifiers

PMID39963554
PMCPMC11832265

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.