Evidence map›Paper›PMID 39963550›Full record

ArticleCancer management and research2025

Clinical Remission Rates in Patients With Epithelial Ovarian Cancer Before and After the Onset of the COVID 19 Pandemic in an Integrated Healthcare Delivery System.

Amrita Mukherjee, Natalie Ayoub, Lanfang Xu, Kimberly L Cannavale, Alec D Gilfillan, Elizabeth A Szamreta, Matthew J Monberg, Melissa Hodeib, Chun R Chao

Abstract read
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Article in Cancer management and research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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0cells of the map it votes in
2citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Amrita MukherjeeDepartment of Research & Evaluation, Kaiser Permanente Southern California, Pasadena, CA, USA.
Natalie AyoubDepartment of Obstetrics and Gynecology, Adventist Health White Memorial Medical Center, Los Angeles, CA, USA.ORCID 0000-0003-2931-5834
Lanfang XuMedHealth Analytics Inc., Sugar Land, TX, USA.
Kimberly L CannavaleDepartment of Research & Evaluation, Kaiser Permanente Southern California, Pasadena, CA, USA.
Alec D GilfillanDepartment of Research & Evaluation, Kaiser Permanente Southern California, Pasadena, CA, USA.
Elizabeth A SzamretaOutcomes Research, Merck & Co., Inc., Rahway, NJ, USA.
Matthew J MonbergOutcomes Research, Merck & Co., Inc., Rahway, NJ, USA.
Melissa HodeibObstetrics & Gynecology Department, Kaiser Permanente Southern California, Riverside, CA, USA.
Chun R ChaoDepartment of Research & Evaluation, Kaiser Permanente Southern California, Pasadena, CA, USA.ORCID 0000-0002-6072-4954

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: Evidence on the impact of the coronavirus disease 2019 (COVID-19) pandemic on outcomes in patients with ovarian cancer patients is limited. We compared remission outcomes in patients with ovarian cancer before and during the pandemic. Patients and Methods: This retrospective cohort study included patients diagnosed with epithelial ovarian cancer between 01/01/2017 and 06/30/2021 at Kaiser Permanente Southern California. Pre and post pandemic periods were designated using March 4, 2020, as the cut-off. Stage I-IV patients who completed chemotherapy and/or surgery as first-line treatment were included. Data on remission outcomes (complete and clinical remission) were abstracted by manual chart reviews. Complete remission was defined as no evidence of disease; clinical remission included both complete and partial response to treatment. Modified Poisson regression was used to evaluate the association of pandemic and remission. Effect modification by race/ethnicity was evaluated. Results: Of 748 ovarian cancer patients included, 72.7% and 27.3% patients were diagnosed before and during the pandemic, respectively. Complete remission was observed in 75.7% and 73.5% patients before and during the pandemic, respectively (p = 0.53). No statistically significant association of pandemic period with remission outcomes was observed in the adjusted models. However, race/ethnicity modified the association of pandemic period with complete remission (p-value < 0.01). White patients, but not other racial/ethnic groups, were 13% more likely to achieve complete remission during the pandemic than during the pre-pandemic [adjusted rate ratio (95% confidence interval): 1.13 (1.00-1.28)]. Conclusion: Patients diagnosed with ovarian cancer achieved similar complete and clinical remission rates before and during the pandemic. Association of the pandemic period with complete remission varied for White vs non-White patients.

Indexed as

clinical remissioncomplete remissionCOVID-19 pandemicovarian cancerrace and ethnicity

Identifiers

PMID39963550
PMCPMC11830944

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.