Evidence map›Paper›PMID 39963475›Full record

ArticleACG case reports journal2025

A Rare Finding of Herpes Simplex Virus Esophagitis Concomitant With Duodenitis in an Immunocompetent Host.

Sergio Sbeih, Gaelle-Christie Haddad, Nicolas Moussallem, Karam, Ihab I El Hajj, Elias Fiani

Abstract readCase Reports
In one paragraph

Article in ACG case reports journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Sergio SbeihDepartment of Internal Medicine, University of Balamand, Beirut, Lebanon.
Gaelle-Christie HaddadDepartment of Internal Medicine, University of Balamand, Beirut, Lebanon.
Nicolas MoussallemDepartment of Internal Medicine, University of Balamand, Beirut, Lebanon.
KaramDepartment of Internal Medicine, University of Balamand, Beirut, Lebanon.
Ihab I El HajjDepartment of Gastroenterology, University of Balamand, Beirut, Lebanon.
Elias FianiDepartment of Gastroenterology, University of Balamand, Beirut, Lebanon.ORCID https://orcid.org/0000-0003-3204-9098

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Herpes simplex virus (HSV) esophagitis and duodenitis are well-known features of herpes virus reactivation in immunosuppressed patients. We discuss the case of HSV esophagitis concomitant with duodenitis in an immunocompetent individual. A 77-year-old male patient, previously healthy, was found to have on upper endoscopy several ulcers in the esophagus and second portion of the duodenum. A diagnosis of HSV esophagitis concomitant with duodenitis was made. The patient was started on intravenous acyclovir, and 48 hours after treatment, his symptoms significantly improved. He was then discharged on acyclovir per os for a total of 14 days. Endoscopy 1 month later showed complete resolution of both esophageal and duodenal ulcers. Physicians should keep the diagnosis of HSV esophagitis with duodenitis in the differentials in the setting of odynophagia, dysphagia, and epigastric pain, even in the case of an immunocompetent individual. Further research is needed to strengthen the literature on this topic.

Indexed as

duodenitisesophagitisherpes simplex virusimmunocompetent

Identifiers

PMID39963475
PMCPMC11832197

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.