ArticleRSC advances2025
Personalised 3D-printed bioactive peek bone plate scaffold for treating femoral defects.
Article in RSC advances, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Metallic topological structures in bone repair implants: Design, properties, and biological interactions.Journal of orthopaedic translation · 2026Review
- Biomaterials-based engineering of the bone microenvironment for osteoporosis therapy.Journal of tissue engineeringReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Fractures affect millions of individuals worldwide, particularly those with osteoporosis, and often require rigid fixation for proper healing. Although traditional metal bone plates are effective, they are limited by their stiffness and inability to conform precisely to anatomical structures, leading to complications such as stress shielding and delayed healing. In this study, we utilized computer-aided design (CAD) combined with reverse engineering to develop a 3D bone plate scaffold model that perfectly matches the contours of the rabbit femur. Additionally, we employed fused deposition modeling (FDM) 3D printing to fabricate a customized polyetheretherketone (PEEK) bone plate scaffold based on the model, designed to match individual bone structures and reduce rigidity-related issues. To enhance the bioactivity of the PEEK scaffold surface, we applied plasma spraying technology to coat it with bioactive materials, including nanohydroxyapatite (HA), tantalum (Ta), and titanium (Ti). The results showed that the HA coating contained 48.06% calcium (Ca) and 16.47% phosphorus (P) and the Ti coating contained 82.32% Ti.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.