A rare case of sporadic metastatic colorectal cancer with glioblastoma multiforme: a challenging clinical scenario.

Farah Awad, Firas Abdallah, Ahmad Alhalabieh, Imad Aljaafreh, Salam Naserallah, Elias Edward Lahham

Abstract readCase Reports

In one paragraph

Article in Journal of surgical case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Farah AwadOncology Department, Augusta Victoria Hospital, East Jerusalem, Palestine.

Firas AbdallahFaculty of Medicine, Al-Quds University, University Street, Abu Dis, Jerusalem District, 9700, Jerusalem, Palestine.

Ahmad AlhalabiehFaculty of Medicine, Al-Quds University, University Street, Abu Dis, Jerusalem District, 9700, Jerusalem, Palestine.

Imad AljaafrehFaculty of Medicine, Al-Quds University, University Street, Abu Dis, Jerusalem District, 9700, Jerusalem, Palestine.

Salam NaserallahFaculty of Medicine, Al-Quds University, University Street, Abu Dis, Jerusalem District, 9700, Jerusalem, Palestine.

Elias Edward LahhamDepartment of Radiation Oncology, Augusta Victoria Hospital, East Jerusalem, Palestine.ORCID https://orcid.org/0000-0002-6514-5206

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Colorectal cancer (CRC) is the third most commonly diagnosed and leading cause of death worldwide. On the other hand, glioblastoma multiforme (GBM) is the most prevalent and aggressive primary malignant brain tumor in adults. Inherited diseases of DNA mismatch repair (MMR) can cause multiple cancers in the same patient including CRC and GBM. In this study, we report a 59-year-old woman presented with fatigue, constipation, abdominal distention, perianal pain, right-sided arm weakness, and personality changes. After investigations, it was diagnosed that sporadic metastatic CRC and GBM occurred simultaneously in the same patient, which was confirmed by colonoscopy, biopsy, imaging, and molecular testing. As the treatment of two cancers in the same patient is unique and complex, the absence of guidelines for such cases was discussed in a multidisciplinary tumor board including surgeons, medical, and radiation oncologists.

Indexed as

colorectal cancerglioblastoma multiformemismatch repair

Identifiers

PMID39963396

DOI10.1093/jscr/rjae708

PMCPMC11831982

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