Evidence map›Paper›PMID 39963301›Full record

ArticleJCEM case reports2025

Use of Olaparib in the Management of Metastatic Parathyroid Carcinoma With

David Woodfield, Trang Le, Grace Prince, Hyun Lee, Hetal Vachhani, Priyanka Majety

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in JCEM case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

David WoodfieldDepartment of Endocrinology, Diabetes, and Metabolism, Virginia Commonwealth University, Richmond, VA 23298, USA.ORCID https://orcid.org/0000-0002-9059-9146
Trang LeDepartment of Endocrinology, Diabetes, and Metabolism, Virginia Commonwealth University, Richmond, VA 23298, USA.
Grace PrinceDepartment of Endocrinology, Diabetes, and Metabolism, Virginia Commonwealth University, Richmond, VA 23298, USA.
Hyun LeeDepartment of Hematology, Oncology, and Palliative Care, Virginia Commonwealth University, Richmond, VA 23298, USA.
Hetal VachhaniDepartment of Hematology, Oncology, and Palliative Care, Virginia Commonwealth University, Richmond, VA 23298, USA.
Priyanka MajetyDepartment of Endocrinology, Diabetes, and Metabolism, Virginia Commonwealth University, Richmond, VA 23298, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Parathyroid carcinoma (PC) is a rare cause of primary hyperparathyroidism with a highly variable clinical course. We report the case of a man with metastatic PC who presented with severe hypercalcemia, discovered incidentally after a fall. He underwent left upper parathyroidectomy with left thyroid lobectomy, and pathology confirmed PC. After a year of absence from follow-up, he developed recurrence with bilateral pulmonary metastases. Cinacalcet and denosumab were initiated due to persistent, severe hypercalcemia, followed by wedge resection and palliative radiotherapy of pulmonary metastases. Genetic analysis revealed no actionable pathogenic variants, but a

Indexed as

BRCAparathyroid carcinomaPARP inhibitor

Identifiers

PMID39963301
PMCPMC11831516

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.