Evidence map›Paper›PMID 39963285›Full record

ReviewFrontiers in endocrinology2025

The agony and the efficacy: central mechanisms of GLP-1 induced adverse events and their mitigation by GIP.

Jonathan D Douros, Jonathan N Flak, Patrick J Knerr

Abstract readReview
In one paragraph

Review in Frontiers in endocrinology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Trial
  2. Improving incretin-mediated body weight loss via energy expenditure.Trends in endocrinology and metabolism: TEM · 2026
    Review
  3. Incretin polyagonists as an alternative to bariatric surgery to manage obesity.World journal of gastrointestinal pathophysiology · 2026
    Review
  4. Article
  5. Review
  6. Article
  7. Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Jonathan D DourosIndiana Biosciences Research Institute, Indianapolis, IN, United States.
Jonathan N FlakIndiana Biosciences Research Institute, Indianapolis, IN, United States.
Patrick J KnerrIndiana Biosciences Research Institute, Indianapolis, IN, United States.

Funding

Defining the neurocircuit activated by the VMH to control energy expenditure.R01DK136897 · NIDDK · INDIANA UNIVERSITY INDIANAPOLIS · PI Jonathan Nicholas Flak · 2023 to 2026
$1.7M
NIDDK NIH HHS R01 DK136897
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

GIP - glucose-dependent insulinotropic peptideGLP-1 - glucagon-like peptide-1incretinobesitypharmacology

Identifiers

PMID39963285
PMCPMC11830610

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.