Evidence map›Paper›PMID 39963272›Full record

ArticleFrontiers in veterinary science2025

Analgesic efficacy of hydromorphone in American alligators (

Scott E Henke, David B Wester, Cord B Eversole, Javier O Huerta, Clayton D Hilton, Kurt K Sladky

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in veterinary science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Scott E HenkeCaesar Kleberg Wildlife Research Institute, Texas A&M University-Kingsville, Kingsville, TX, United States.
David B WesterCaesar Kleberg Wildlife Research Institute, Texas A&M University-Kingsville, Kingsville, TX, United States.
Cord B EversoleArthur Temple College of Forestry and Agriculture, Stephen F. Austin State University, Nacogdoches, TX, United States.
Javier O HuertaCaesar Kleberg Wildlife Research Institute, Texas A&M University-Kingsville, Kingsville, TX, United States.
Clayton D HiltonCaesar Kleberg Wildlife Research Institute, Texas A&M University-Kingsville, Kingsville, TX, United States.
Kurt K SladkyDepartment of Surgical Sciences, School of Veterinary Medicine, University of Wisconsin, Madison, WI, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: American alligators ( Objective: The objective of this study was to determine the analgesic efficacy of hydromorphone in alligators. Methods: Female American alligators ( Results: Administration of hydromorphone contributed to a range from 62 to 92% reduced avoidance reactions to mechanical noxious stimuli for two anatomic sites (i.e., naris and lateral mandible, respectively). Conclusion: Alligators did not appear to experience clinically relevant respiratory depression, hypothermia, or other adverse reactions. Therefore, hydromorphone shows promise as an analgesic option to be administered under painful conditions in American alligators.

Indexed as

Alligator mississippiensisAmerican alligatoranalgesiahydromorphonenociceptionpain managementreptilevon Frey

Identifiers

PMID39963272
PMCPMC11830746

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.