Evidence map›Paper›PMID 39963254›Full record

ArticleBiomaterials and biosystems2025

Development of fully-resorption replacement paste-like organic/inorganic artificial bones compatible with bone remodeling cycles.

Yuki Kamaya, Shiori Kato, Kazuaki Nakano, Masaki Nagaya, Hiroshi Nagashima, Mamoru Aizawa

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomaterials and biosystems, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yuki KamayaDepartment of Applied Chemistry, School of Science and Technology, Meiji University, 1-1-1 Higashimita, Tama-ku, Kawasaki 214-8571, Kanagawa, Japan.
Shiori KatoDepartment of Applied Chemistry, School of Science and Technology, Meiji University, 1-1-1 Higashimita, Tama-ku, Kawasaki 214-8571, Kanagawa, Japan.
Kazuaki NakanoMeiji University International Institute for Bio-Resource Research (MUIIBR), 1-1-1 Higashimita, Tama-ku, Kawasaki 214-8571, Kanagawa, Japan.
Masaki NagayaMeiji University International Institute for Bio-Resource Research (MUIIBR), 1-1-1 Higashimita, Tama-ku, Kawasaki 214-8571, Kanagawa, Japan.
Hiroshi NagashimaMeiji University International Institute for Bio-Resource Research (MUIIBR), 1-1-1 Higashimita, Tama-ku, Kawasaki 214-8571, Kanagawa, Japan.
Mamoru AizawaDepartment of Applied Chemistry, School of Science and Technology, Meiji University, 1-1-1 Higashimita, Tama-ku, Kawasaki 214-8571, Kanagawa, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Calcium-phosphate cement (CPC), commonly used as a bone graft substitute, sets as hydroxyapatite (HAp) and remains in the body for extended periods. To enhance bioresorbabability, we developed a chelate-setting tricalcium β-phosphate (β-TCP) cement using inositol phosphate (IP6) surface modification. By incorporating poly(lactic-co-glycolic acid) (PLGA) particles as a pore-forming agent and calcium sulfate hemihydrate (CSH) to this CPC, we created an organic/inorganic hybrid cement combining bioresorbability with favorable material properties. In this study, varying amounts of PLGA particles were added alongside CSH, and the resulting cement's properties, cytotoxicity, and

Indexed as

BioresorbabilityBone-forming abilityBone remodeling cyclePaste-like artificial bonePoly (lactic-co-glycolic acid) particlesβ-tricalcium phosphate

Identifiers

PMID39963254
PMCPMC11830353

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.