Evidence map›Paper›PMID 39962944›Full record

ArticleEpilepsia2025

Portable ultra-low-field magnetic resonance imaging enables postictal seizure imaging.

Tobias Bauer, Hemmen Sabir, Tobias Baumgartner, Attila Rácz, Jan Pukropski, Mostafa Badr, Simon Olbrich, Annalena Lange, Justus Bisten, Anne Groteklaes and 5 more

Abstract read
In one paragraph

Article in Epilepsia, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Seminars in epileptology: Presurgical epilepsy evaluation.Epileptic disorders : international epilepsy journal with videotape · 2025
    Review
  4. Review
  5. Article
  6. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Tobias BauerDepartment of Neuroradiology, University Hospital Bonn, Bonn, Germany.ORCID https://orcid.org/0000-0002-0555-6214
Hemmen SabirGerman Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.
Tobias BaumgartnerDepartment of Epileptology, University Hospital Bonn, Bonn, Germany.ORCID https://orcid.org/0000-0001-5935-9841
Attila RáczDepartment of Epileptology, University Hospital Bonn, Bonn, Germany.
Jan PukropskiDepartment of Epileptology, University Hospital Bonn, Bonn, Germany.ORCID https://orcid.org/0000-0002-8280-6475
Mostafa BadrDepartment of Epileptology, University Hospital Bonn, Bonn, Germany.
Simon OlbrichDepartment of Neuroradiology, University Hospital Bonn, Bonn, Germany.
Annalena LangeDepartment of Neuroradiology, University Hospital Bonn, Bonn, Germany.
Justus BistenDepartment of Neuroradiology, University Hospital Bonn, Bonn, Germany.
Anne GroteklaesDepartment of Neonatology and Pediatric Intensive Care, University Hospital Bonn, Bonn, Germany.
Nils C LehnenDepartment of Neuroradiology, University Hospital Bonn, Bonn, Germany.
Fernando CendesDepartment of Neurology, University of Campinas, Campinas, Brazil.ORCID https://orcid.org/0000-0001-9336-9568
Alexander RadbruchDepartment of Neuroradiology, University Hospital Bonn, Bonn, Germany.
Rainer SurgesDepartment of Epileptology, University Hospital Bonn, Bonn, Germany.
Theodor RüberDepartment of Neuroradiology, University Hospital Bonn, Bonn, Germany.ORCID https://orcid.org/0000-0002-6180-7671

Funding

Neuro-aCSis 2024-12-07UNITY Consortium
6 · The paper itself

Abstract

The detection of transient peri-ictal magnetic resonance imaging (MRI) abnormalities has been variable after epileptic seizures. The most common reason for this variability is that abnormalities may disappear if the interval between seizure and scan acquisition is prolonged using conventional high-field systems. Here, we deployed a portable ultra-low-field MRI system in the presurgical evaluation at the bedside of individuals with epilepsy. We hypothesized that this novel technology enables rapid postictal scans and reliably shows focal peri-ictal MRI abnormalities in the seizure onset zone. A .064-T Swoop Portable MR Imaging System was used. Postictally, an axial diffusion-weighted sequence was acquired. The interictal MRI consisted of the diffusion-weighted and three-dimensional T1-weighted sequences. Postictal-interictal difference maps of diffusion-weighted volumes were calculated. Three individuals were included. Two individuals with focal aware seizures scanned 29 s and 19 min after the seizure, respectively, showed focal restrictions in diffusivity in the seizure onset zone, and a third individual scanned 5 h 45 min after a focal to bilateral tonic-clonic seizure showed global restrictions of diffusivity. Portable ultra-low-field MRI opens a new line of inquiry with the aim to establish postictal seizure imaging as part of the presurgical evaluation of people with epilepsy.

Indexed as

BrainMagnetic Resonance ImagingSeizuresAdultDiffusion Magnetic Resonance ImagingElectroencephalographyFemaleHumansMaleMiddle AgedYoung Adultcortical localizationdiffusion imagingepilepsy surgeryfunctional neuroimagingglobal epileptology

Identifiers

PMID39962944
PMCPMC11997907

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.