ArticleBMC health services research2025
Exploring the financial burden of pediatric bone marrow transplantation: a cross-sectional Study from the caregiver's viewpoint.
Article in BMC health services research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Stem cell transplantation cost in Iran.BMC health services research · 2025Article
- Cell therapy in pediatric blood diseases.Frontiers in medicine · 2025Review
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND AND
aimBone marrow transplantation is an expensive treatment procedure that result in financial burdens. The aim of this study was to assess the financial burdens of this procedure from the caregiver's viewpoint. MATERIAL AND
methodThis cross-sectional study included pediatric patients (under 18 years old) who underwent hematopoietic cell transplantation March 21, 2017, and March 21, 2019. A checklist was designed for interview and data collection. A comprehensive review of articles in PubMed, Embase and web of science and scientific texts was conducted. The checklist comprises 25 items, of which 11 pertain to the demographic characteristics of the patient's guardian, three items are dedicated to the child's medical condition, and remaining items focus on the financial implications of the transplant, such as its impact on employment and bank savings, selling or exchanging assets to cover costs, receiving charitable support, economizing on essential and non-essential expenses, borrowing money to cover transplant expenses, and downgrading one's standard of living to afford the transplant.
resultsA total of 257 caregivers of pediatric patients who were underwent hematopoietic cell transplantation (HCT) were interviewed. The majority of respondents (92%) were parents of patients. The predominant type of HCT among patients was allogeneic (82.9%). Patients underwent HCT for 17 different diseases, with the most common being thalassemia (18.7%) and acute lymphoblastic leukemia (ALL) (16.7%). About 18% of the respondents stated that they had to take leave from work to pursue transplantation for their patients. Additionally, 19.5% of the participants reported that they had to work part-time due to the demands of the treatment process, while about 18% were completely unemployed in order to follow the treatment process of their patients. 92% of caregivers were forced to spend all of their bank savings to cover HCT expenses. Furthermore, 67% of respondents stated that they were forced to sell their assets to cover HCT expenses, with gold and jewelry being the most commonly sold assets by households (38.5% or 99 people).
conclusionDespite the lower cost of bone marrow transplantation in Iran compared to developed countries, the purchasing power of people and the insurance coverage should be taken into account. This study revealed that the financial burden on Iranian caregivers is substantial and leads to severe economic impacts and deterioration of households' quality of life. Therefore, policy and insurance reforms are needed to improve the situation of bone marrow transplantations.
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