Evidence map›Paper›PMID 39962221›Full record

ArticleScientific reports2025

Associations of excessive gestational weight gain with changes in components of maternal reverse cholesterol transport and neonatal outcomes.

Minja Derikonjic, Jelena Vekic, Aleksandra Stefanovic, Marija Saric Matutinovic, Jelena Munjas, Tamara Antonic, Marija Mitrovic, Daniela Ardalic, Marko Stankovic, Tamara Gojkovic and 6 more

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In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Minja DerikonjicDepartment of Medical Biochemistry, University of Belgrade-Faculty of Pharmacy, Vojvode Stepe 450, Belgrade, 11000, Serbia. minja.derikonjic@pharmacy.bg.ac.rs.
Jelena VekicDepartment of Medical Biochemistry, University of Belgrade-Faculty of Pharmacy, Vojvode Stepe 450, Belgrade, 11000, Serbia.
Aleksandra StefanovicDepartment of Medical Biochemistry, University of Belgrade-Faculty of Pharmacy, Vojvode Stepe 450, Belgrade, 11000, Serbia.
Marija Saric MatutinovicDepartment of Medical Biochemistry, University of Belgrade-Faculty of Pharmacy, Vojvode Stepe 450, Belgrade, 11000, Serbia.
Jelena MunjasDepartment of Medical Biochemistry, University of Belgrade-Faculty of Pharmacy, Vojvode Stepe 450, Belgrade, 11000, Serbia.
Tamara AntonicDepartment of Medical Biochemistry, University of Belgrade-Faculty of Pharmacy, Vojvode Stepe 450, Belgrade, 11000, Serbia.
Marija MitrovicDepartment of Medical Biochemistry, University of Belgrade-Faculty of Pharmacy, Vojvode Stepe 450, Belgrade, 11000, Serbia.
Daniela ArdalicGynecology and Obstetrics Clinic Narodni Front, Kraljice Natalije 62, Belgrade, 11000, Serbia.
Marko StankovicGynecology and Obstetrics Clinic Narodni Front, Kraljice Natalije 62, Belgrade, 11000, Serbia.
Tamara GojkovicDepartment of Medical Biochemistry, University of Belgrade-Faculty of Pharmacy, Vojvode Stepe 450, Belgrade, 11000, Serbia.
Milica Miljkovic TrailovicDepartment of Medical Biochemistry, University of Belgrade-Faculty of Pharmacy, Vojvode Stepe 450, Belgrade, 11000, Serbia.
Jasmina IvanisevicDepartment of Medical Biochemistry, University of Belgrade-Faculty of Pharmacy, Vojvode Stepe 450, Belgrade, 11000, Serbia.
Natasa Bogavac StanojevicDepartment of Medical Biochemistry, University of Belgrade-Faculty of Pharmacy, Vojvode Stepe 450, Belgrade, 11000, Serbia.
Snezana JovicicDepartment of Medical Biochemistry, University of Belgrade-Faculty of Pharmacy, Vojvode Stepe 450, Belgrade, 11000, Serbia.
Zeljko MikovicGynecology and Obstetrics Clinic Narodni Front, Kraljice Natalije 62, Belgrade, 11000, Serbia.
Aleksandra ZeljkovicDepartment of Medical Biochemistry, University of Belgrade-Faculty of Pharmacy, Vojvode Stepe 450, Belgrade, 11000, Serbia.

Funding

Ministry of Science, Technological Development and Innovation, Republic of Serbia 451-03-65/2024-03/ 200161 and 451-03-66/2024-03/ 200161Science Fund of the Republic of Serbia 7741659
6 · The paper itself

Abstract

Excessive gestational weight gain may be associated with unfavorable pregnancy outcomes. We explored the impact of excessive weight gain on components of HDL metabolism in maternal plasma: sterol composition of HDL particles, distribution of HDL subclasses and SCARB1, ABCA1 and ABCG1 genes expressions and their associations with newborns' characteristics. The study included 124 pregnant women, 58 with recommended and 66 with excessive weight gain. Concentrations of cholesterol synthesis marker, desmosterol, within HDL increased during pregnancy in both groups of participants. In women with excessive weight gain, levels of cholesterol absorption marker, campesterol, within HDL were significantly lower in the 3

Indexed as

CholesterolGestational Weight GainAdultATP Binding Cassette Transporter 1ATP Binding Cassette Transporter, Subfamily G, Member 1Biological TransportBody Mass IndexCholesterol, HDLDesmosterolFemaleHumansInfant, NewbornLipoproteins, HDLPhytosterolsPregnancyPregnancy OutcomeABCA1 protein, humanABCG1 protein, humanATP Binding Cassette Transporter 1ATP Binding Cassette Transporter, Subfamily G, Member 1campesterolCholesterolCholesterol, HDLDesmosterolLipoproteins, HDLPhytosterolsSCARB1 protein, humanScavenger Receptors, Class BSitosterolsCholesterol synthesis and absorption markersGestational weight gainHDL subclassesNewborns’ characteristicsSCARB1

Identifiers

PMID39962221
PMCPMC11832930

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.