ArticleScientific reports2025
Association between cardiovascular health and overactive bladder.
Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
4 citing papers in PubMed.
- A retrospective cross-sectional study on the nonlinear association between cardiovascular health and overactive bladder in a national population-based cohort.Annals of medicine and surgery (2012) · 2026Article
- Elevated urinary succinate in women with symptom-defined overactive bladder without clinically recognized cardiometabolic disease: a cross-sectional study.BMC women's health · 2026Article
- Association between social determinants of health and overactive bladder: exploring the role of cardiovascular health in a cross-sectional analysis.BMC public health · 2026Article
- Sleep matters: the U-shaped relationship between sleep duration and overactive bladder in U.S. adults.Frontiers in medicine · 2025Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Life's Essential 8 (LE8) is an emerging composite metric of cardiovascular health encompassing diet, physical activity, smoking, sleep, weight, cholesterol, blood glucose, and blood pressure. Mounting evidence suggests lifestyle factors may play an important role in overactive bladder (OAB), however the link between LE8 and OAB remains unexplored. We aimed to examine the correlation between the two. We analyzed data on 23,187 individuals from the 2005-2018 National Health and Nutrition Examination Survey (NHANES). Participants were stratified into low, moderate and high LE8 groups. Logistic regression examined the association between LE8 and OAB. Restricted cubic splines (RCS) and weighted quantile sum (WQS) regression further probed this relationship. Higher LE8 scores were associated with lower OAB risk, independent of covariate adjustment. The inverse correlation between LE8 and OAB was validated by RCS and WQS analyses. Of LE8 components, glycemic control conferred the greatest contribution. Higher LE8 scores may be protective against OAB. Optimization of cardiovascular health metrics could represent a novel OAB prevention strategy.
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Registered trials
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