ArticleNature communications2025
A biodegradable and restorative peripheral neural interface for the interrogation of neuropathic injuries.
Article in Nature communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Advancements in Machine Learning-Assisted Flexible Electronics: Technologies, Applications, and Future Prospects.Biosensors · 2026Pooled it
- Multifunctional material platforms for neural interfaces: active orchestration of dynamic foreign body response across implantation lifetimes.Bioactive materials · 2026Review
- Artificial intelligence and peripheral neuropathies: Strategies for the development, application, and repair of regenerative biomaterials.Neural regeneration research · 2026Article
- Biointegrated Battery-Based Electroceuticals.Advanced materials (Deerfield Beach, Fla.) · 2026Review
- Multiscale biomimetic design for peripheral nerve repair: Beyond passive bridging.Materials today. Bio · 2026Review
- Engineering halogen-doped carbon dots for enhanced bioinspired synapses toward neuromorphic computing and neural interfaces.Materials today. Bio · 2026Article
- Harnessing spatiotemporal melatonin delivery from engineered platforms for targeted microenvironment remodeling in peripheral neuropathy.Materials today. Bio · 2026Review
- Multi-Functional Adaptive Interfaces for Next-Generation Wearable and Implantable Bioelectronics.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Review
- Multi-Channel Neural Interface for Neural Recording and Neuromodulation.Small methods · 2026Review
- Flexible Polymer-Based Electronics for Human Health Monitoring: A Safety-Level-Oriented Review of Materials and Applications.Nano-micro letters · 2026Review
- A self-wrapping, bioresorbable neural interface for wireless multimodal therapy of localized peripheral nerve injury.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Biodegradable Implantable Electronics with Wireless Technology for Real-Time Clinical Applications.Advanced healthcare materials · 2026Review
- Autonomous Polymer Frameworks for Sustainable Tissue-Interfaced Plastic Bioelectronics.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Review
- Multidimensional advances in neural interface technology for peripheral nerve repair: From material innovation to clinical translation.Materials today. Bio · 2025Review
- Biodegradable Medical Implants: Reshaping Future Medical Practice.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Review
- Bioresorbable electrodes in implantable electronic healthcare devices.Frontiers in bioengineering and biotechnology · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
24 authors.
Funding
Abstract
Monitoring the early-stage healing of severe traumatic nerve injuries is essential to gather physiological and pathological information for timely interventions and optimal clinical outcomes. Traditional diagnostic methods relying on physical examinations, imaging tools, and intraoperative electrophysiological testing present great challenges in continuous and remote monitoring. While implantable peripheral nerve interfaces provide direct access to nerve fibers for precise interrogation and modulation, conventional non-degradable designs pose limited utilization in nerve injury rehabilitation. Here, we introduce a biodegradable and restorative neural interface for wireless real-time tracking and recovery of long-gap nerve injuries. Leveraging machine learning techniques, this electronic platform deciphers nerve recovery status and identifies traumatic neuroma formation at the early phase, enabling timely intervention and significantly improved therapeutic outcomes. The biodegradable nature of the device eliminates the need for retrieval procedures, reducing infection risks and secondary tissue damage. This research sheds light on bioresorbable multifunctional peripheral nerve interfaces for probing neuropathic injuries, offering vital information for early diagnosis and therapeutic intervention.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.