Evidence map›Paper›PMID 39962029›Full record

ArticleInsights into imaging2025

Exploratory high b value diffusion-weighted MR for quantitative differentiation of ileocecal inflammatory conditions and tumors.

Hao Yu, Yucheng Hai, Jingyu Lu

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Article in Insights into imaging, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed
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1 · What the graph read from it

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3 · Its place in the literature

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1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

3 authors.

Hao YuDepartment of Radiology, Zhongnan Hospital of Wuhan University, Wuhan, China. zn003969@whu.edu.cn.ORCID http://orcid.org/0000-0002-4450-5137
Yucheng HaiDepartment of Radiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Jingyu LuDepartment of Radiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

Funding

National Natural Science Foundation of China 82102026
6 · The paper itself

Abstract

objectivesTo explore the quantitative analysis of high b value (2000 s/mm

methodsSixty-six patients with 30 tumors and 36 inflammatory conditions underwent MR enterography with conventional and high b values DWI. Quantitative apparent diffusion coefficient (ADC) values and signal intensity ratios (SIRs) of lesions of the psoas muscle were measured from the two b value DWIs. The receiver operating characteristic (ROC) curve was applied to determine the diagnostic value of ADC and SIR for differentiating tumors from inflammatory conditions.

resultsThe ADC values of tumors were significantly lower than those of inflammatory conditions in 800 s/mm

conclusionsQuantitative ADC values and SIR could be used as non-invasive tools to distinguish ileocecal tumors from inflammatory conditions. The use of high b value DWI would improve this ability. Furthermore, SIR obtained from high b value DWI was the most promising quantitative parameter. CRITICAL RELEVANCE STATEMENT: This study indicated that quantitative DWI parameters might be applied as non-invasive imaging biomarkers for distinguishing bowel tumors from inflammatory conditions. The SIR from high b value DWI could improve the differentiation, providing invaluable information for establishing appropriate therapeutic strategies. KEY POINTS: Differentiation between bowel inflammatory conditions and tumors is still a dilemma. Quantitative DWI contributed to distinguishing ileocecal tumors from inflammatory conditions. SIR from DWI is a promising parameter for differentiating these pathologies.

Indexed as

Diffusion-weighted imagingHigh b valueInflammationTumor

Identifiers

PMID39962029
PMCPMC11833009

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