ArticleJournal of epidemiology and global health2025
Pre-Operative Markers of Post-Operative Complications in Pancreatic Cancer Patients: A Single-Center Study.
Article in Journal of epidemiology and global health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Comparative analysis of survival outcomes and prognostic factors between intrahepatic and extrahepatic cholangiocarcinoma after surgical resection: a propensity score-matched study based on the SEER database.Langenbeck's archives of surgery · 2026Article
- Inpatient Outcomes of Pancreatic Cancer Surgery in Patients with Coronary Artery Disease.Cancers · 2026Article
- Nutritional Risk Assessment of Patients Undergoing Pancreaticoduodenectomy After Standardization of Preoperative Nutritional Support.Nutrients · 2025Article
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4 authors.
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Abstract
purposePancreatic cancer remains a deadly disease with a low survival rate specifically if diagnosed at later stages. Surgery is one of the mainstay treatments for early stage disease but is accompanied by significant mortality and morbidity even in high volume centers. In the present study we wanted to determine the influence of pre-operative weight loss, BMI and liver function tests on postoperative outcomes.
methodsData for patients who underwent pancreatic surgery at the American University of Beirut Medical Center between 1998 and 2017 were analyzed. The data included patient demographics, pathologic diagnosis, stage, nodal involvement, tumor grade, surgical margin, type of adjuvant therapy, liver function tests and post-operative complications. The correlation and p-value were determined by the chi-square test with p-value < 0.05 considered statistically significant.
resultsThe analysis included 236 patients. 63% were males and mean age was 60 years. A total of 96 (41%) patients had significant weight loss prior to surgery and 173 (31%) had a BMI > 30 kg/m2 which were considered obese. Obesity and significant weight loss were associated with increased risk of post-operative complications (P = 0.013 and P = 0.004, respectively). Transaminases and cholestatic liver enzymes were not associated with post-operative complications.
conclusionsAssessment and management of nutritional status particularly weight loss and BMI prior to pancreatic cancer surgery may influence postoperative outcomes in this patient population.
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