Evidence map›Paper›PMID 39961965›Full record

ArticleDigestive diseases and sciences2025

Challenges in Promoting Physical Activity for Managing MASLD in Canadian Children: Insights and Barriers.

Mohit Kehar, Lina Huerta-Saenz, Jamie Strain, Sierra Kawesa, Jenna Yaraskavitch, Jonathan Stine, Patricia E Longmuir

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Article in Digestive diseases and sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Mohit KeharDivision of Pediatric Gastroenterology, Hepatology and Nutrition, Children's Hospital of Eastern Ontario, University of Ottawa, Ottawa, Canada. mkehar@cheo.on.ca.
Lina Huerta-SaenzDivision of Pediatric Endocrinology and Diabetes, Department of Pediatrics, Penn State Health Children's Hospital, Penn State College of Medicine, Hershey, PA, USA.
Jamie StrainDivision of Pediatric Gastroenterology, Hepatology and Nutrition, Children's Hospital of Eastern Ontario, University of Ottawa, Ottawa, Canada.
Sierra KawesaDivision of Pediatric Gastroenterology, Hepatology and Nutrition, Children's Hospital of Eastern Ontario, University of Ottawa, Ottawa, Canada.
Jenna YaraskavitchFaculty of Medicine and Faculty of Health Sciences, Children's Hospital of Eastern Ontario Research Institute, University of Ottawa, Ottawa, Canada.
Jonathan Stine *Division of Gastroenterology & Hepatology, Department of Medicine and Department of Public Health Sciences, Penn State Health- Milton S. Hershey Medical Center, Penn State Cancer Institute, Hershey, PA, USA.
Patricia E Longmuir *Faculty of Medicine and Faculty of Health Sciences, Children's Hospital of Eastern Ontario Research Institute, University of Ottawa, Ottawa, Canada.

Funding

Establishing the mechanism of benefit and dose of exercise required to improve liver histology in patients with nonalcoholic steatohepatitisK23DK131290 · NIDDK · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI STINE, JONATHAN G · 2022 to 2025
$801k
NIDDK NIH HHS K23 DK131290
6 · The paper itself

Abstract

backgroundMetabolic dysfunction-associated steatotic liver disease (MASLD) is the most common chronic liver disease in children, closely linked to the rise in pediatric obesity. Physical activity (PA) is critical for MASLD management, yet many children fail to meet PA guidelines due to various barriers. This study quantifies PA levels and identifies barriers in Canadian children with MASLD.

methodsThis prospective cohort study included 25 pediatric MASLD patients (≤ 18 years) recruited from a tertiary care center between spring and fall 2023. Participants completed the Habitual Activity Estimation Scale (HAES) and a modified PA Barrier Survey. Clinical, demographic, and laboratory data were collected.

resultsThe median age was 13 years, with 64% male participants. While 96% recognized the importance of PA, only 56% met the WHO-recommended 60 min of daily moderate-to-vigorous PA. Barriers included fatigue (84%), discomfort (56%), fear of injury (32%), and ridicule (36%). Participants who met PA guidelines were more likely to feel supported by healthcare providers (79% vs. 45%). Moderate technology use (52% used activity trackers) suggests potential for greater integration to boost engagement.

conclusionChildren with MASLD face significant barriers to PA despite high awareness of its benefits. Tailored strategies incorporating technology and healthcare support are essential to improving PA adherence. Future research should explore larger cohorts and the influence of socioeconomic and cultural factors on PA behaviors.

Indexed as

ExerciseHealth PromotionNon-alcoholic Fatty Liver DiseaseAdolescentCanadaChildFemaleHumansMaleProspective StudiesBarriersCanadian childrenMetabolic dysfunction-associated steatotic liver diseasePediatricPhysical activity

Identifiers

PMID39961965

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.