Evidence map›Paper›PMID 39961872›Full record

ArticlePlant cell reports2025

Prime editing via precise sequence insertion restores function of the recessive rc allele in rice.

Cuong X Nguyen, Trong D Nguyen, Thao T Dinh, Linh T Nguyen, Linh K Ly, Ha H Chu, Thang C La, Phat T Do

Abstract read
PubMed Publisher
In one paragraph

Article in Plant cell reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Cuong X NguyenDepartment of Plant Cell Technology, Institute of Biotechnology, Vietnam Academy of Science and Technology, Hanoi, Vietnam. cuongxnguyen2020@gmail.com.ORCID http://orcid.org/0000-0002-8580-5865
Trong D NguyenDepartment of Plant Cell Technology, Institute of Biotechnology, Vietnam Academy of Science and Technology, Hanoi, Vietnam.
Thao T DinhDepartment of Plant Cell Technology, Institute of Biotechnology, Vietnam Academy of Science and Technology, Hanoi, Vietnam.
Linh T NguyenDepartment of Plant Cell Technology, Institute of Biotechnology, Vietnam Academy of Science and Technology, Hanoi, Vietnam.
Linh K LyDepartment of Plant Cell Technology, Institute of Biotechnology, Vietnam Academy of Science and Technology, Hanoi, Vietnam.
Ha H ChuDepartment of Plant Cell Technology, Institute of Biotechnology, Vietnam Academy of Science and Technology, Hanoi, Vietnam.
Thang C LaDepartment of Crop Science, College of Agriculture, Can Tho University, Can Tho, Vietnam.
Phat T DoDepartment of Plant Cell Technology, Institute of Biotechnology, Vietnam Academy of Science and Technology, Hanoi, Vietnam.

Funding

Vietnam Academy of Science and Technology THTNTE.01/24-25
6 · The paper itself

Abstract

key messageAn improved prime editing system precisely corrected a 14-bp deletion in the rc gene of white rice, restoring the production of brown pigments.

Indexed as

Gene EditingGenes, RecessiveMutagenesis, InsertionalOryzaPlant ProteinsAllelesBase SequenceCRISPR-Cas SystemsGenes, PlantPlants, Genetically ModifiedPlant ProteinsColoration riceFunctional restorationPrime editingRc,rdTwinPE

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.