Evidence map›Paper›PMID 39961851›Full record

ArticleIntensive care medicine2025

ESICM consensus-based recommendations for the management of very old patients in intensive care.

Michael Beil, Laura Alberto, Richard S Bourne, Nathan E Brummel, Bas de Groot, Dylan W de Lange, Paul Elbers, Marielle Emmelot-Vonk, Hans Flaatten, Yonathan Freund and 22 more

Erratum issuedAbstract readConsensus Statement
PubMed Publisher
In one paragraph

Article in Intensive care medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed.

  1. Recognise, respond, reflect: A value-based framework for rapid response teams.Critical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine · 2026
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

32 authors.

Michael BeilDepartment of Medicine, NHS Highland, Inverness, UK. beil@doctors.org.uk.ORCID 0009-0005-1845-657X
Laura AlbertoConsejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Instituto de Investigación en Medicina y Ciencias de la Salud, Universidad del Salvador, Ciudad de Buenos Aires, Argentina.
Richard S BourneDepartments of Pharmacy and Critical Care, Sheffield Teaching Hospitals NHS Foundation Trust, Herries Road, Sheffield, UK.
Nathan E BrummelDivision of Pulmonary, Critical Care and Sleep Medicine, The Ohio State University College of Medicine, The Ohio State University Wexner Medical Center, Columbus, OH, USA.
Bas de GrootDepartment of Emergency Medicine, Radboud UMC, Nijmegen, The Netherlands.
Dylan W de LangeDepartment of Intensive Care Medicine, University Medical Center, University Utrecht, Utrecht, The Netherlands.
Paul ElbersDepartment of Intensive Care Medicine, Center for Critical Care Computational Intelligence, Amsterdam UMC, Vrije Universiteit, Amsterdam, The Netherlands.
Marielle Emmelot-VonkDepartment of Geriatrics, University Medical Center Utrecht, Utrecht, The Netherlands.
Hans FlaattenDepartment of Research and Development, Haukeland University Hospital, Bergen, Norway.
Yonathan FreundSorbonne Université, IMProving Emergency Care (IMPEC) FHU, Emergency Department, Hôpital Pitié-Salpêtrière, Assistance Publique-Hôpitaux de Paris, Paris, France.
Alessandro GalazziDepartment of Medicine, University of Udine, Udine, Italy.
Ana Garcia-MartinezEmergency Department, Hospital Clínic, IDIBAPS, Barcelona, Spain.
Bertrand GuidetSorbonne Universités, UPMC Univ Paris 06, INSERM, UMR_S 1136, Institut Pierre Louis d'Epidémiologie et de Santé Publique, Equipe: Épidémiologie Hospitalière Qualité et Organisation des Soins, Paris, France.
Iva HolmerovaCentre of Gerontology, Centre of Expertise in Longevity and Long-Term Care, Faculty of Humanities, Charles University, Prague, Czech Republic.
Jeremy M JacobsDepartment of Geriatric Rehabilitation and Center for Palliative Care, Hadassah Medical Center and Faculty of Medicine, Hebrew University of Jerusalem, Jerusalem, Israel.
Gavin M JoyntDepartment of Anaesthesia and Intensive Care, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, China.
Susannah LeaverGeneral Intensive Care, St George's University Hospitals NHS Foundation Trust, London, UK.
Marc LeoneDepartment of Anesthesiology and Intensive Care Unit, Assistance Publique-Hopitaux Universitaires de Marseille, Aix Marseille University, Marseille, France.
Bairbre McNicholasDepartment of Anaesthesia and Intensive Care Medicine, Galway University Hospital, Galway, Ireland.
David McWilliamsCentre for Care Excellence, Coventry University, Coventry, UK.
Victoria MetaxaDepartment of Critical Care, King's College Hospital NHS Foundation Trust, London, UK.
Christian H NickelEmergency Department, University Hospital, University of Basel, Basel, Switzerland.
Daniele PooleOperative Unit of Pain Therapy. S. Martino Hospital, Belluno, Italy.
Chiara RobbaDipartimento di Scienze Chirurgiche Diagnostiche ed Integrate, IRCCS Policlinico San Martino, University of Genoa, Genoa, Italy.
Kevin RoedlDepartment of Intensive Care Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Marc RomainDepartment of Medical Intensive Care, Hadassah Medical Center, Faculty of Medicine, Hebrew University of Jerusalem, Jerusalem, Israel.
Anne-Françoise RousseauIntensive Care Department, University Hospital of Liège, Research Unit for a Life-Course Perspective on Health and Education-RUCHE, University of Liège, Liège, Belgium.
Sigal SviriDepartment of Medical Intensive Care, Hadassah Medical Center and Faculty of Medicine, Hebrew University of Jerusalem, Jerusalem, Israel.
Wojciech SzczeklikCenter for Intensive Care and Perioperative Medicine, Jagiellonian University Medical College, Krakow, Poland.
Helene ValletService de Gériatrie Aigue/UPREG, Hôpital Saint Antoine, Assistance Publique-Hôpitaux de Paris, Sorbonne Université, UMRS 1135-Institut National de la Santé et de la Recherche Médicale (INSERM), Centre d'Immunologie et de Maladies Infectieuses (CIMI), Paris, France.
James van OppenCentre for Urgent and Emergency Care Research, University of Sheffield, Sheffield, UK.
Christian JungDepartment of Cardiology, Pulmonology and Vascular Medicine and Cardiovascular Research Institute Düsseldorf (CARID), Heinrich-Heine-University Duesseldorf, Medical Faculty, Duesseldorf, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe heterogeneity of very old patients (age ≥ 80 years) and the prevalence of complex geriatric syndromes in this cohort constitute major challenges for the classical methods of evidence-based medicine to inform clinical practice. The lack of robust guidance for the management of critical conditions in these patients contributes to considerable uncertainty among practitioners and unwarranted variations of care. The European Society of Intensive Care Medicine (ESICM) initiated a Delphi study to translate the empirical knowledge of experts in this field into consensus-based recommendations for clinical practice.

methodsA multi-national group of specialists in intensive care, emergency, and geriatric medicine provided opinions on managing very old patients with critical conditions. Strong or moderate consensus was defined as having at least 90% or 80% of experts, respectively, expressing agreement or disagreement on the three highest or lowest levels of a 9-points Likert scale.

resultsTwenty-eight members of the expert steering group and 82 additional experts completed two Delphi rounds. After discussing the results, the steering group issued recommendations for 48 statements and 2 checklists for which consensus was achieved. In addition to determining fundamental principles, they include advice on goals of care and the decision-making about admission to and treatment of patients in intensive care and the management after discharge.

conclusionA multi-disciplinary group of experts achieved consensus on recommendations concerning intensive care for very old patients, which were approved and endorsed by ESICM. The implementation requires a careful analysis of available healthcare resources and should proceed in a stepwise fashion.

Indexed as

Critical CareGeriatricsAged, 80 and overDelphi TechniqueEuropeHumansCritical careDelphi studyEmergency medicineGeriatric medicineIntensive care

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.