Evidence map›Paper›PMID 39961813›Full record

ReviewDermatologie (Heidelberg, Germany)2025

[Differential diagnosis of epidermotropic neoplasia].

Rose K C Moritz, Franziska C Ghoreschi

Abstract readEnglish AbstractReview
PubMed Publisher
In one paragraph

Review in Dermatologie (Heidelberg, Germany), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Rose K C MoritzKlinik für Dermatologie, Venerologie und Allergologie, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Charitéplatz 1, 10117, Berlin, Deutschland. rose.moritz@charite.de.
Franziska C GhoreschiKlinik für Dermatologie, Venerologie und Allergologie, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Charitéplatz 1, 10117, Berlin, Deutschland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Many benign and malignant neoplasms may involve the epidermis, a phenomenon which is commonly referred to as epidermotropism. Intraepidermal localization is an important diagnostic clue. However, differentiation of neoplastic cells can be challenging, especially when the cells are completely confined to the epidermis. Besides the large group of lymphoid and melanocytic neoplasms, several rare entities may show epidermotropism. Typical examples are mammary and extramammary Paget's disease and Langerhans cell histiocytosis. Other rare differential diagnoses include Merkel cell carcinoma, granular cell tumor, adnexal tumors, and epidermotropic metastases. The Borst-Jadassohn phenomenon describes the mimicry of epidermotropic neoplasia in Bowen's disease, Bowenoid actinic keratosis, clonal seborrheic keratosis, and hidroacanthoma simplex. Inflammatory dermatoses with increased intraepidermal localization of immune cells may mimic intraepidermal neoplasia. We review the different entities and summarize the key morphologic and immunohistochemical features for diagnosis.

Indexed as

EpidermisSkin NeoplasmsDiagnosis, DifferentialHistiocytosis, Langerhans-CellHumansDifferential diagnosisEpidermotropismImmunohistochemistryIntraepidermal neoplasiaMorphology

Identifiers

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.