ArticleArchives of microbiology2025
Effects of bcsE, luxS and rfaG genes on the physiology and pathogenicity of Salmonella Typhimurium.
Article in Archives of microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Biosurfactant-Mediated Inhibition ofMicroorganisms · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In this study, rfaG, luxS, and bcsE gene mutants of S. Typhimurium ATCC 14028 wild-type strain were generated, and their effects on bacterial physiology and pathogenicity were investigated. Biofilm production capacity and mobility of mutant strains were found to be significantly reduced. Immune response stimulation of 6-8 week-old BALB/c mice infected with wild-type and mutants was evaluated on days 0 and 21 for IL-6, IFN-γ, and IgG, and then systemic infection in mice was determined by the amount of Salmonella recovered from the cecum, spleen, and liver organs. The specific IgG antibody level and the expression level of the cytokines IFN-γ and IL-6 were found to be significantly reduced in mice inoculated with mutant strains compared to the control group. The highest level of colonization in the organs was found in the cecum, and the lowest level of colonization was detected in the liver. In the wild-type-infected group, splenomegaly and staining of the liver were detected. In the groups of mice infected with bcsE and luxS mutants, these symptoms were at a low level. In the groups infected with the rfaG mutant, no significant lesions were detected in the organs.
Indexed as
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.