Evidence map›Paper›PMID 39961703›Full record

ArticleOpen heart2025

Cost-effectiveness of a community first responder system for out-of-hospital cardiac arrest in Belgium.

Bianca de Greef, Cornelia Genbrugge, Sanjay Verma, Goran Medic, Joachim Maurer, Tom A Kooy, Olivier Hoogmartens, Marc Sabbe

Abstract read
In one paragraph

Article in Open heart, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Bianca de GreefChief Medical Office - Health Economics and Outcome Research, Philips, Amsterdam, Netherlands bianca.de.greef@philips.com.ORCID http://orcid.org/0000-0003-1698-1301
Cornelia GenbruggeEmergency Department, University Hospitals Leuven, Leuven, Vlaams-Brabant, Belgium.
Sanjay VermaChief Medical Office - Health Economics and Outcome Research, Philips, Amsterdam, Netherlands.
Goran MedicChief Medical Office - Health Economics and Outcome Research, Philips, Amsterdam, Netherlands.
Joachim MaurerConnected Care - Emergency Care, Philips, Amsterdam, Netherlands.
Tom A KooyResearch and Development Department, Stan B.V, Nunspeet, Netherlands.
Olivier HoogmartensDepartment of Public Health and Primary Care, KU Leuven Leuven Institute for Healthcare Policy, Leuven, Flanders, Belgium.
Marc SabbeEmergency Department, University Hospitals Leuven, Leuven, Vlaams-Brabant, Belgium.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveOut-of-hospital cardiac arrest (OHCA) is a major public health challenge across Europe, with a survival rate of only 8.5% to hospital discharge. Implementing a community first responder (CFR) system, including earlier Basic Life Support and defibrillation, can enhance survival rates and neurological outcomes. This study assesses the cost-effectiveness of two scenarios for implementing such a system in Belgium.

methodsA decision tree and the long-term Markov model were used to evaluate cost-effectiveness by comparing two scenarios with current care standards. Scenario 1 involved an awareness campaign on OHCA, while Scenario 2 included implementing a CFR system with automated external defibrillator (AED) integration, dispatch centre linkage and training for citizen responders. The analysis covered survival to the emergency department, hospital, discharge and neurologically intact survival, with sensitivity analyses to test robustness.

resultsThe awareness campaign and implementation of the CFR system resulted in an incremental cost-effectiveness ratio of €14,976 and €16,442 per quality-adjusted life year gained for scenarios 1 and 2, respectively. Both scenarios showed improvements in survival rates at various stages, including hospital discharge and neurologically intact survival.

conclusionThis study highlights the benefits of enhancing Belgium's CFR for OHCA patients. It suggests that accessible AEDs, trained CFRs and an integrated emergency response system could improve survival rates and quality of life. These findings can guide policy and resource decisions, potentially improving the effectiveness and cost-efficiency of OHCA emergency services. Additionally, this approach could serve as a model for other regions aiming to strengthen their response to time-sensitive emergencies.

Indexed as

Cardiopulmonary ResuscitationCommunity Health ServicesElectric CountershockEmergency Medical ServicesEmergency RespondersHealth Care CostsOut-of-Hospital Cardiac ArrestBelgiumCost-Benefit AnalysisDecision TreesDefibrillatorsFemaleHumansMaleMarkov ChainsMiddle AgedDefibrillators, ImplantableHealth Care Economics and OrganizationsOutcome Assessment, Health CareOut-of-Hospital Cardiac ArrestQuality of Health Care

Identifiers

PMID39961703
PMCPMC11836846

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.