Evidence map›Paper›PMID 39961285›Full record

ArticleVox sanguinis2025

Implementation of a blood proficiency testing scheme for bacterial screening of platelet components.

Marcel Prax, Lea Debes, Michael Chudy, Angela Filomena, Giulio Pisani, Simonetta Pupella, Marie Riley, Daniele Sondag-Thull, Marie-Laure Hecquet, Marie Pierre Emery and 2 more

Abstract read
In one paragraph

Article in Vox sanguinis, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Marcel PraxInfectiology/Serology, Paul-Ehrlich-Institut (PEI), Langen, Germany.ORCID https://orcid.org/0000-0003-0974-2265
Lea DebesInfectiology/Serology, Paul-Ehrlich-Institut (PEI), Langen, Germany.
Michael ChudyInfectiology/Serology, Paul-Ehrlich-Institut (PEI), Langen, Germany.
Angela FilomenaInfectiology/Serology, Paul-Ehrlich-Institut (PEI), Langen, Germany.
Giulio PisaniItalian National Blood Centre, Italian National Institute of Health (ISS), Rome, Italy.
Simonetta PupellaNational Centre for the Control and Evaluation of Medicines, Italian National Institute of Health (ISS), Rome, Italy.
Marie RileyQuality Assurance, National Blood Transfusion Service, Pietà, Malta.
Daniele Sondag-ThullService du Sang, Croix-Rouge de Belgique, Suarlée, Belgium.
Marie-Laure HecquetIntergovernmental Committees and Networks Department (ICND), European Directorate for the Quality of Medicines & HealthCare (EDQM), Strasbourg, France.
Marie Pierre EmeryIntergovernmental Committees and Networks Department (ICND), European Directorate for the Quality of Medicines & HealthCare (EDQM), Strasbourg, France.ORCID https://orcid.org/0009-0003-9982-3532
Marie PfliegerIntergovernmental Committees and Networks Department (ICND), European Directorate for the Quality of Medicines & HealthCare (EDQM), Strasbourg, France.
Perrine ArnouldIntergovernmental Committees and Networks Department (ICND), European Directorate for the Quality of Medicines & HealthCare (EDQM), Strasbourg, France.

Funding

EDQM, Council of EuropeEuropean Commission
6 · The paper itself

Abstract

BACKGROUND AND

objectivesThe European Directorate for the Quality of Medicines & HealthCare has been co-ordinating an external quality assessment programme for blood establishment (BE) laboratories since 2010. To further expand the study portfolio, a new bacterial blood proficiency testing scheme (B-PTS) for platelet components (PCs) has been developed and validated in a pilot study. MATERIALS AND

methodsSterile samples and those containing a low-count quantity of bacteria were prepared in spiking devices. Suitability of storage and shipping conditions for the samples was evaluated under different environmental conditions. Participants received the spiking devices, prepared the potentially contaminated PCs on site and tested them according to their routine screening procedures.

resultsHumidity compromised the quality of the samples. Optimized storage of the samples by adding a desiccant ensured satisfactory quality. In the pilot study, 9 of the 11 participants correctly identified the positive samples as being bacterially contaminated.

conclusionThe newly developed bacterial B-PTS was successfully implemented in a pilot study. It enables an inter-laboratory comparison to determine the performance of BEs for the testing of bacterial contaminations in PCs.

Indexed as

BacteriaBlood PlateletsLaboratory Proficiency TestingHumansPilot Projectsbacteriablood safetycontaminationplateletsproficiency testingquality control

Identifiers

PMID39961285
PMCPMC12017949

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.