Evidence map›Paper›PMID 39960983›Full record

ReviewCirculation2025

Hypertension in Pregnancy and Postpartum: Current Standards and Opportunities to Improve Care.

Malamo Countouris, Zainab Mahmoud, Jordana B Cohen, Daniela Crousillat, Afshan B Hameed, Colleen M Harrington, Alisse Hauspurg, Michael C Honigberg, Jennifer Lewey, Kathryn Lindley and 10 more

Abstract readReview
In one paragraph

Review in Circulation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
54citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

54 citing papers in PubMed, 1 synthesis or guideline pooled it.

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  9. Pregnancy as a Window for Hypertension and Cardiovascular Prevention in Women: A Life-Course Perspective Based on the 2025 ESC Guidelines.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Malamo Countouris *Department of Medicine, Division of Cardiology (M.C.), PA.ORCID 0000-0003-2535-0309
Zainab Mahmoud *Department of Medicine, Division of Cardiology, Washington University in St Louis, MO (Z.M., K.E.W.).ORCID 0000-0002-5203-2253
Jordana B CohenRenal-Electrolyte and Hypertension Division, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia (J.B.C.).ORCID 0000-0003-4649-079X
Daniela CrousillatDepartment of Medicineand Obstetrics and Gynecology, Division of Cardiovascular Sciences, University of South Florida Morsani College of Medicine, Tampa General Hospital Heart and Vascular Institute (D.C.).
Afshan B HameedUniversity of Pittsburgh (A.H.), PA.
Colleen M HarringtonDepartment of Medicine, Division of Cardiology, Women's Heart Health Program, Massachusetts General Hospital, Boston (C.M.H., M.C.H., A.S.).
Michael C HonigbergDepartment of Medicine, Division of Cardiology, Women's Heart Health Program, Massachusetts General Hospital, Boston (C.M.H., M.C.H., A.S.).ORCID 0000-0001-8630-5021
Kathryn LindleyDepartment of Medicine, Division of Cardiology, Vanderbilt University Medical Center, Nashville, TN (K.L.).ORCID 0000-0002-8504-0006
Megan M McLaughlinDepartment of Medicine, Division of Cardiology, University of California San Francisco (M.M.M.).ORCID 0000-0002-9259-2984
Neha SachdevAmerican Medical Association, Chicago, IL (N.S.).ORCID 0000-0002-4899-7570
Amy SarmaDepartment of Medicine, Division of Cardiology, Women's Heart Health Program, Massachusetts General Hospital, Boston (C.M.H., M.C.H., A.S.).
Kayle ShaperoBrown University Health Cardiovascular Institute (K.S.), Alpert Medical School of Brown University, Providence, RI.ORCID 0000-0002-7747-4410
Rachel SinkeyCenter for Women's Reproductive Health (R.S., A.T.), University of Alabama at Birmingham.ORCID 0000-0001-7674-9796
Alan TitaCenter for Women's Reproductive Health (R.S., A.T.), University of Alabama at Birmingham.
Kristen E WongDepartment of Medicine, Division of Cardiology, Washington University in St Louis, MO (Z.M., K.E.W.).ORCID 0000-0002-7497-9835
Eugene YangDepartment of Medicine, Division of Cardiology, University of Washington School of Medicine, Seattle (E.Y.).ORCID 0000-0003-3945-7529
Leslie Cho *Department of Cardiovascular Medicine, Heart Vascular Thoracic Institute at the Cleveland Clinic, OH (L.C.).ORCID 0000-0002-1190-1774
Natalie A Bello *Department of Cardiology, Smidt Heart Institute, Cedars-Sinai Medical Center, Los Angeles, CA (N.A.B.).ORCID 0000-0003-3257-3623

Funding

Obesity Prevention in Postpartum Women at High-Risk of Cardiovascular DiseaseK23HL153667 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI LEWEY, JENNIFER · 2020 to 2024
$926k
The ACHIEVE Trial: Achieving longer gestation in preeclampsia via antihypertensive therapy.K23HL159331 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Rachel G Sinkey · 2022 to 2026
$884k
NHLBI NIH HHS K23 HL153667NHLBI NIH HHS K23 HL159331
6 · The paper itself

Abstract

Hypertension in pregnancy contributes substantially to maternal morbidity and mortality, persistent hypertension, and rehospitalization. Hypertensive disorders of pregnancy are also associated with a heightened risk of cardiovascular disease, and timely recognition and modification of associated risk factors is crucial in optimizing long-term maternal health. During pregnancy, there are expected physiologic alterations in blood pressure (BP); however, pathophysiologic alterations may also occur, leading to preeclampsia and gestational hypertension. The diagnosis and effective management of hypertension during pregnancy is essential to mitigate maternal risks, such as acute kidney injury, stroke, and heart failure, while balancing potential fetal risks, such as growth restriction and preterm birth due to altered uteroplacental perfusion. In the postpartum period, innovative and multidisciplinary care solutions that include postpartum maternal health clinics can help optimize short- and long-term care through enhanced BP management, screening of cardiovascular risk factors, and discussion of lifestyle modifications for cardiovascular disease prevention. As an adjunct to or distinct from postpartum clinics, home BP monitoring programs have been shown to improve BP ascertainment across diverse populations and to lower BP in the months after delivery. Because of concerns about pregnant patients being a vulnerable population for research, there is little evidence from trials examining the diagnosis and treatment of hypertension in pregnant and postpartum individuals. As a result, national and international guidelines differ in their recommendations, and more studies are needed to bolster future guidelines and establish best practices to achieve optimal cardiovascular health during and after pregnancy. Future research should focus on refining treatment thresholds and optimal BP range peripartum and postpartum and evaluating interventions to improve postpartum and long-term maternal cardiovascular outcomes that would advance evidence-based care and improve outcomes worldwide for people with hypertensive disorders of pregnancy.

Indexed as

HypertensionHypertension, Pregnancy-InducedPostpartum PeriodPregnancy Complications, CardiovascularAntihypertensive AgentsBlood PressureFemaleHumansPregnancyRisk FactorsAntihypertensive Agentsblood pressurehypertensionpostpartum periodpre-eclampsiapregnancytelemedicine

Identifiers

PMID39960983
PMCPMC11973590

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.