Evidence map›Paper›PMID 39960970›Full record

ReviewMedicine2025

The role of pharmacological interventions in managing urological complications during pregnancy and childbirth: A review.

Isaac Edyedu, Okechukwu Paul-Chima Ugwu, Chinyere N Ugwu, Esther Ugo Alum, Val Hyginus Udoka Eze, Mariam Basajja, Jovita Nnenna Ugwu, Fabian Chukwudi Ogenyi, Regina Idu Ejemot-Nwadiaro, Michael Ben Okon and 3 more

Abstract readReview
In one paragraph

Review in Medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Isaac EdyeduFaculty of Clinical Medicine Kampala International University, Kampala, Uganda.
Okechukwu Paul-Chima UgwuDepartment of Publication and Extension, Kampala International University, Kampala, Uganda.ORCID 0000-0003-3563-3521
Chinyere N UgwuDepartment of Publication and Extension, Kampala International University, Kampala, Uganda.
Esther Ugo AlumDepartment of Publication and Extension, Kampala International University, Kampala, Uganda.
Val Hyginus Udoka EzeDepartment of Publication and Extension, Kampala International University, Kampala, Uganda.
Mariam BasajjaHealth Care and Data Management Leiden University, Kampala, Uganda.
Jovita Nnenna UgwuDepartment of Publication and Extension, Kampala International University, Kampala, Uganda.
Fabian Chukwudi OgenyiDepartment of Publication and Extension, Kampala International University, Kampala, Uganda.
Regina Idu Ejemot-NwadiaroDepartment of Public Health, School of Allied Health Sciences, Kampala International University, Kampala, Uganda.
Michael Ben OkonDepartment of Publication and Extension, Kampala International University, Kampala, Uganda.
Simeon Ikechukwu EgbaDepartment of Publication and Extension, Kampala International University, Kampala, Uganda.
Daniel Ejim UtiDepartment of Publication and Extension, Kampala International University, Kampala, Uganda.
Patrick Maduabuchi AjaDirectorate of Research, Innovation, Consultancy and Extension (RICE), Kampala International University, Kampala, Uganda.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pregnancy leads to a number of structural and functional changes in the urinary system, which makes females susceptible to urological complications. This review aims to discuss the epidemiology, complications and prevention and management of urinary tract infections (UTIs), kidney stones and bladder dysfunction in pregnancy. UTIs are the most common urological problem presenting in 10% of pregnant women; Escherichia coli is the most common causative organism. If left untreated, UTIs lead to acute pyelonephritis which occurs in about 2% of pregnant women and which has serious consequences for both the mother and the baby. Kidney stones, although rare, are hazardous, occurring in 1 in 200 to 1 in 1500 pregnancies, and may cause obstructive uropathy, and aggravation of "labor-like" pain. Urological complications are frequent in pregnancy; bladder dysfunction alone has been documented to affect 50% of the pregnant women. Urological complications can have severe consequences when not properly managed including preterm labor and renal dysfunction. In order to have the best pharmacological care, safe use of antibiotics for UTIs is needed along with other measures for kidney stones. This review highlights the importance of a team approach to patient management to optimize outcome and touches briefly on some of the ethical dilemmas that may be encountered when drug therapy in pregnancy is being considered. Therefore, it is feasible to enhance the health of women and the fetus during this period through patient focused care and innovative interventions.

Indexed as

Anti-Bacterial AgentsPregnancy ComplicationsPregnancy Complications, InfectiousUrinary Tract InfectionsFemaleHumansKidney CalculiPregnancyAnti-Bacterial Agents

Identifiers

PMID39960970
PMCPMC11835077

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.