Evidence map›Paper›PMID 39960950›Full record

ReviewMedicine2025

Symmetrical peripheral gangrene after cardiac surgery: A case report and review of literature.

Xiaoliang Chen, Guofeng Shao, Shunying Zhao, Ni Li

Abstract readCase ReportsReview
In one paragraph

Review in Medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Xiaoliang ChenDepartment of Cardiosurgery Intensive Care Unit, Ningbo Medical Centre Lihuili Hospital, Ningbo University, Ningbo, China.ORCID 1924-5611-3618-1762
Guofeng ShaoDepartment of Cardiothoracic Surgery, Ningbo Medical Centre Lihuili Hospital, Ningbo University, Ningbo, China.
Shunying ZhaoDepartment of Cardiosurgery Intensive Care Unit, Ningbo Medical Centre Lihuili Hospital, Ningbo University, Ningbo, China.
Ni LiDepartment of Cardiothoracic Surgery, Ningbo Medical Centre Lihuili Hospital, Ningbo University, Ningbo, China.

Funding

Ningbo Top Medical and Health Research Program 2022030107Zhejiang Medical and Health Science and Technology Plan Project 2024KY298
6 · The paper itself

Abstract

rationaleCardiac surgery can cause arrhythmias and low cardiac output syndrome through various mechanisms, including cardiac manipulation, systemic inflammation, myocardial hypoxia, cardioplegic arrest, and ischemia resulting from coronary or graft occlusion. Symmetric peripheral gangrene is a rare but serious complication that can occur after cardiac surgery. Here, we present a case of symmetric peripheral gangrene shortly after cardiac surgery for mitral valve replacement. PATIENT CONCERNS: A 76-year-old male with rheumatic heart disease and severe mitral stenosis underwent mitral valve replacement. He experienced postoperative bleeding on the first day after the cardiac surgery. After experiencing ventricular fibrillation, cardiogenic shock, acute hepatic failure, and disseminated intravascular coagulation (DIC), he developed symmetrical peripheral gangrene on the fifth day after cardiac surgery. DIAGNOSES: The patient presented with postoperative bleeding, cardiogenic shock, and DIC complicated by symmetrical peripheral gangrene following cardiac surgery.

interventionsDuring cardiosurgery intensive care unit admission, the patient received positive inotropic agents and vasopressors, blood transfusion, and antithrombotic treatment with low -molecular-weight heparin. Because of the severe general condition of the patient, amputation was not performed. OUTCOMES: The patient died on the 80th day after cardiac surgery because of multiorgan failure and DIC. LESSONS: Physicians should be vigilant for comorbid symmetrical peripheral gangrene in patients undergoing cardiac surgery who present with postoperative bleeding, cardiogenic shock, and DIC. Early recognition of acrocyanosis, prompt management of cardiogenic shock, correction of anemia, hemodynamic stabilization, and properly controlled use of anticoagulation may help prevent symmetrical peripheral gangrene.

Indexed as

Cardiac Surgical ProceduresGangreneHeart Valve Prosthesis ImplantationPostoperative ComplicationsAgedDisseminated Intravascular CoagulationFatal OutcomeHumansMaleMitral Valve StenosisMultiple Organ FailurePostoperative HemorrhageRheumatic Heart DiseaseShock, Cardiogenic

Identifiers

PMID39960950
PMCPMC11835120

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.