Evidence map›Paper›PMID 39960587›Full record

ArticleAdvances in therapy2025

Surgical Outcomes of Baerveldt Glaucoma Implant Versus Ahmed Glaucoma Valve in Neovascular Glaucoma: A Retrospective Multicenter Study.

Kentaro Iwasaki, Sachi Kojima, Ryotaro Wajima, Akira Matsuda, Koki Yoshida, Aika Tsutsui, Michihiro Kono, Miho Nozaki, Koji Namiguchi, Keisuke Nitta and 6 more

Abstract readMulticenter StudyComparative Study
In one paragraph

Article in Advances in therapy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Clinical outcomes of the PAUL Glaucoma implant for neovascular glaucoma.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2025
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Kentaro IwasakiDepartment of Ophthalmology, Faculty of Medical Sciences, University of Fukui, 23-3 Shimoaizuki, Matsuoka, Eiheiji, Yoshida, Fukui, 910-1193, Japan.
Sachi KojimaDepartment of Ophthalmology, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan.
Ryotaro WajimaDepartment of Ophthalmology, Kanazawa University Graduate School of Medical Science, Ishikawa, Japan.
Akira MatsudaDepartment of Ophthalmology, Juntendo University School of Medicine, Tokyo, Japan.
Koki YoshidaDepartment of Ophthalmology, Toho University Ohashi Medical Center, Tokyo, Japan.
Aika TsutsuiDepartment of Ophthalmology, Shimane University Faculty of Medicine, Shimane, Japan.
Michihiro KonoDepartment of Ophthalmology, Shimane University Faculty of Medicine, Shimane, Japan.
Miho NozakiDepartment of Ophthalmology and Visual Science, Nagoya City University Graduate School of Medical Sciences, Aichi, Japan.
Koji NamiguchiDepartment of Ophthalmology, Ehime University Graduate School of Medicine, Ehime, Japan.
Keisuke NittaDepartment of Ophthalmology, Gunma University Graduate School of Medicine, Gunma, Japan.
Yusaku MiuraDepartment of Ophthalmology and Visual Science, Kochi Medical School, Kochi University, Kochi, Japan.
Toshihiro InoueDepartment of Ophthalmology, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan.
Tomomi HigashideDepartment of Ophthalmology, Kanazawa University Graduate School of Medical Science, Ishikawa, Japan.
Kyoko IshidaDepartment of Ophthalmology, Toho University Ohashi Medical Center, Tokyo, Japan.
Masaki TanitoDepartment of Ophthalmology, Shimane University Faculty of Medicine, Shimane, Japan.
Masaru InataniDepartment of Ophthalmology, Faculty of Medical Sciences, University of Fukui, 23-3 Shimoaizuki, Matsuoka, Eiheiji, Yoshida, Fukui, 910-1193, Japan. inatani@u-fukui.ac.jp.ORCID 0000-0003-0896-996X

Funding

Japan Society for the Promotion of Science 20H03840Japan Society for the Promotion of Science 22K16967Japan Society for the Promotion of Science 22K19582
6 · The paper itself

Abstract

introductionThis multicenter retrospective study compared the surgical outcomes of Baerveldt glaucoma implant (BGI) surgery with those of Ahmed glaucoma valve (AGV) surgery in patients with neovascular glaucoma (NVG).

methodsThe study included patients with NVG aged ≥ 20 years who had undergone BGI (223 eyes) or AGV (146 eyes) surgery between April 1, 2012 and December 31, 2021 across 10 clinical centers in Japan. Surgical success or failure was the primary outcome measure of this study. We defined surgical failure as a reduction of < 20% in the pre-operative intraocular pressure (IOP) or criterion A (IOP > 21 mmHg), criterion B (IOP > 17 mmHg), or criterion C (IOP > 14 mmHg). In addition, we considered a requirement for re-operation, loss of light perception, and hypotony as surgical failure.

resultsThe surgical success rate of the BGI surgery group was significantly higher than that of the AGV group for criteria A (P = 0.01) and B (P = 0.01). Multivariate analysis revealed that AGV surgery showed significant associations with surgical failure for criteria A (hazard ratio, 1.74), B (hazard ratio, 1.72), and C (hazard ratio, 1.34). The overall incidence of postoperative complications was comparable between the two groups. The requirement for re-operation in the AGV surgery group was significantly higher than that in the BGI surgery group (12.3% vs. 5.8%, P = 0.03).

conclusionsBGI surgery yielded a higher success rate than AGV surgery in patients with NVG for a target IOP of < 21 or < 17 mmHg. No significant differences were observed between the two procedures in terms of the incidence of postoperative complications. Additional glaucoma surgery was required more frequently following AGV surgery. Therefore, BGI surgery may be a more suitable and efficacious option for the management of IOP in patients with neovascular glaucoma compared with AGV surgery.

Indexed as

Glaucoma Drainage ImplantsGlaucoma, NeovascularAdultAgedAged, 80 and overFemaleHumansIntraocular PressureJapanMaleMiddle AgedPostoperative ComplicationsRetrospective StudiesTreatment OutcomeAhmed glaucoma valveBaerveldt glaucoma implantIntraocular pressureMulticenterNeovascular glaucomaSurgical outcomes

Identifiers

PMID39960587
PMCPMC11929686

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.