Evidence map›Paper›PMID 39960530›Full record

ArticleNeuroradiology2025

Eighteen-year journey in endovascular management of cavernous sinus DAVFs: advances, outcomes, and lessons learned.

Amedeo Cervo, Branko Popadic, Antonio Macera, Claudia Rollo, Luca Quilici, Luca Valvassori, Mariangela Piano, Camillo Sherif, Edoardo Boccardi, Guglielmo Pero

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Article in Neuroradiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Amedeo CervoASST Grande Ospedale Metropolitano Niguarda, Milan, Italy.
Branko PopadicUniversity Hospital, St. Poelten, Austria.
Antonio MaceraASST Grande Ospedale Metropolitano Niguarda, Milan, Italy.
Claudia RolloASST Grande Ospedale Metropolitano Niguarda, Milan, Italy.
Luca QuiliciOspedale Papa Giovanni XXIII, Bergamo, Italy.
Luca ValvassoriOspedale San Carlo, Potenza, Italy.
Mariangela PianoASST Grande Ospedale Metropolitano Niguarda, Milan, Italy.
Camillo SherifUniversity Hospital, St. Poelten, Austria.
Edoardo BoccardiASST Grande Ospedale Metropolitano Niguarda, Milan, Italy.
Guglielmo PeroASST Grande Ospedale Metropolitano Niguarda, Milan, Italy. guglielmo.pero@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThis study presents a long-term single-centre experience with CS-DAVFs and discusses the historical progression, current state, and future directions of endovascular treatment.

methodsWe retrospectively reviewed all patients with CS-DAVFs endovascularly treated at our institution between 2006 and 2024. We evaluated clinical presentation, imaging findings, endovascular treatment techniques, and clinical improvement.

results63 patients underwent 68 endovascular procedures. 49 patients (72%) underwent transvenous procedures through the inferior petrosal sinus or ophthalmic veins. 39 fistulas (57%) were occluded using liquid embolic agents (LEAs) alone or in combination with coils. Eight patients (12%) required the injection of LEAs in the superior pharyngeal branch of the APA to reach the complete occlusion of the fistula. In 4 cases, the vascular anatomy of the fistula required the direct puncture of the draining vein. In 46 cases (68%), the fistula was successfully occluded using coils. Complete occlusion was achieved in 52 of the cases (77%), but two cases (3%) had fistula recurrence after the first treatment. We found one complication of the endovascular procedure in the study population. The median imaging follow-up time was 12 months (range 2-135); the median clinical follow-up was 32 months (range 1.5-194). 60 Patients (95%) showed persistent clinical improvement.

conclusionsEndovascular occlusion is the gold standard for CS-DAVFs, with high rates of occlusion and few complications. Continued advancements in techniques and devices are essential to improve outcomes and reduce complications.

Indexed as

Cavernous SinusCentral Nervous System Vascular MalformationsEmbolization, TherapeuticEndovascular ProceduresAdultAgedCerebral AngiographyFemaleHumansMaleMiddle AgedRetrospective StudiesTreatment OutcomeAscending pharyngeal arteryCavernous sinusDural arteriovenous fistulaEmbolizationEndovascular treatmentLiquid embolic agents

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.