Evidence map›Paper›PMID 39960349›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2025

Transformable Tumor Microenvironment-Responsive Oxygen Vacancy-Rich MnO

Minxing Li, Qiyu Liu, Songzuo Xie, Desheng Weng, Jinjun He, Xinyi Yang, Yuanyuan Liu, Jinqi You, Jinghao Liao, Peng Wang and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Transformable Tumor Microenvironment-Responsive Oxygen Vacancy-Rich MnOAdvanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Minxing LiState Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Collaborative Innovation Center for Cancer Medicine, Department of Biotherapy, Sun Yat-Sen University Cancer Center, Guangzhou, 510060, P. R. China.
Qiyu LiuThe Key Lab of Low-carbon Chem & Energy Conservation of Guangdong Province, School of Chemistry, Sun Yat-Sen University, Guangzhou, 510275, P. R. China.
Songzuo XieState Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Collaborative Innovation Center for Cancer Medicine, Department of Biotherapy, Sun Yat-Sen University Cancer Center, Guangzhou, 510060, P. R. China.
Desheng WengState Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Collaborative Innovation Center for Cancer Medicine, Department of Biotherapy, Sun Yat-Sen University Cancer Center, Guangzhou, 510060, P. R. China.
Jinjun HeThe Key Lab of Low-carbon Chem & Energy Conservation of Guangdong Province, School of Chemistry, Sun Yat-Sen University, Guangzhou, 510275, P. R. China.
Xinyi YangState Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Collaborative Innovation Center for Cancer Medicine, Department of Biotherapy, Sun Yat-Sen University Cancer Center, Guangzhou, 510060, P. R. China.
Yuanyuan LiuState Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Collaborative Innovation Center for Cancer Medicine, Department of Biotherapy, Sun Yat-Sen University Cancer Center, Guangzhou, 510060, P. R. China.
Jinqi YouState Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Collaborative Innovation Center for Cancer Medicine, Department of Biotherapy, Sun Yat-Sen University Cancer Center, Guangzhou, 510060, P. R. China.
Jinghao LiaoState Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Collaborative Innovation Center for Cancer Medicine, Department of Biotherapy, Sun Yat-Sen University Cancer Center, Guangzhou, 510060, P. R. China.
Peng WangDepartment of Emergency Medicine, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, 510120, P. R. China.
Xihong LuThe Key Lab of Low-carbon Chem & Energy Conservation of Guangdong Province, School of Chemistry, Sun Yat-Sen University, Guangzhou, 510275, P. R. China.ORCID https://orcid.org/0000-0002-6764-0024
Jingjing ZhaoState Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Collaborative Innovation Center for Cancer Medicine, Department of Biotherapy, Sun Yat-Sen University Cancer Center, Guangzhou, 510060, P. R. China.

Funding

Guangdong Basic and Applied Basic Research Foundation 2021A1515010443Guangdong Basic and Applied Basic Research Foundation 2023A1515012467National Natural Science Foundation of China 82272239
6 · The paper itself

Abstract

Despite the promise of sonodynamic therapy (SDT)-mediated immunotherapy, the anticancer efficacy of current sonosensitizers is greatly limited by the immunosuppressive tumor microenvironment (TME) and their inability to selectively respond to it. Herein, oxygen vacancy-rich MnO

Indexed as

DurapatiteImmunotherapyManganese CompoundsNanospheresNeoplasmsOxidesTumor MicroenvironmentUltrasonic TherapyAnimalsCell Line, TumorHumansMiceMice, Inbred BALB COxygenDurapatiteManganese Compoundsmanganese dioxideOxidesOxygenimmunotherapyreactive oxygen speciessonodynamic therapysonosensitizerstumor microenvironment

Identifiers

PMID39960349
PMCPMC11984894

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.