Evidence map›Paper›PMID 39959988›Full record

ReviewDevelopment (Cambridge, England)2025

The dynamics of tubulogenesis in development and disease.

Adrian Romero, Brandy L Walker, Vanja Krneta-Stankic, Kamryn Gerner-Mauro, Lydia Youmans, Rachel K Miller

Abstract readReview
In one paragraph

Review in Development (Cambridge, England), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Adrian RomeroDepartment of Pediatrics, Pediatric Research Center, UTHealth McGovern Medical School, Houston, TX 77030, USA.
Brandy L WalkerDepartment of Pediatrics, Pediatric Research Center, UTHealth McGovern Medical School, Houston, TX 77030, USA.
Vanja Krneta-StankicDepartment of Pediatrics, Pediatric Research Center, UTHealth McGovern Medical School, Houston, TX 77030, USA.
Kamryn Gerner-MauroDepartment of Pulmonary Medicine, Division of Internal Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
Lydia YoumansDepartment of Pediatrics, Pediatric Research Center, UTHealth McGovern Medical School, Houston, TX 77030, USA.
Rachel K MillerDepartment of Pediatrics, Pediatric Research Center, UTHealth McGovern Medical School, Houston, TX 77030, USA.ORCID 0000-0001-6381-7198

Funding

NRSA Training CoreTL1TR003169 · NCATS · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI CHANDRA, JOYA, FROST, JEFFREY A. · 2019 to 2023
$3.7M
Novel Role of Nephron Epithelialization in Nuclear SignalingR01DK115655 · NIDDK · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI Rachel Katherine Miller · 2019 to 2026
$2.3M
Research Training of Anesthesiology Physician-ScientistsT32GM135118 · NIGMS · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI Holger K. Eltzschig, Cynthia Ju · 2022 to 2026
$1.1M
CTSA Predoctoral T32 at the University of Texas Health Science Center at HoustonT32TR004905 · NCATS · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI Joya Chandra, Jeffrey A. Frost · 2024 to 2026
$811k
Center for Clinical and Translational Sciences, University of Texas Health Science Center at Houston TL1TR003169 T32TR004905NCATS NIH HHS T32 TR004905NCATS NIH HHS TL1 TR003169NIDDK NIH HHS R01 DK115655NIDDK NIH HHS R01DK115655NIGMS NIH HHS T32 GM135118NIGMS NIH HHS T32GM135118University of Texas Health Science Center at Houston Graduate School of Biomedical SciencesUniversity of Texas MD Anderson Cancer Center
6 · The paper itself

Abstract

Tubes are crucial for the function of many organs in animals given their fundamental roles in transporting and exchanging substances to maintain homeostasis within an organism. Therefore, the development and maintenance of these tube-like structures within organs is a vital process. Tubes can form in diverse ways, and advances in our understanding of the molecular and cellular mechanisms underpinning these different modes of tubulogenesis have significant impacts in many biological contexts, including development and disease. This Review discusses recent progress in understanding developmental mechanisms underlying tube formation.

Indexed as

OrganogenesisAnimalsHumansSignal TransductionCell polarityLumenMechanical forcesMorphogenesisTubulogenesis

Identifiers

PMID39959988
PMCPMC11883272

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.