ArticleArtificial organs2025
Ex Vivo Preservation of Porcine Vascularized Composite Soft Tissue Allografts.
Article in Artificial organs, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Time as a Therapeutic Ally: The Promise of Long-Term Solid Organ and Tissue Perfusion.Transplant international : official journal of the European Society for Organ Transplantation · 2026Review
Corrections and comments
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Authors and funding
14 authors.
Funding
Abstract
introductionThe aim of this study was to evaluate ex vivo perfusion (EVP) for vascularized composite tissue preservation. We hypothesized that EVP could maintain allografts in near-physiologic conditions for ≥ 24 h.
methodsTwenty superior epigastric artery perforator-based abdominal flaps were procured from 10 Yorkshire pigs. Flaps were preserved for 12 h (n = 5) or 24 h (n = 5) using EVP with an oxygenated colloid solution containing HBOC-201 oxygen carrier (HbO
resultsIschemia time was 16 ± 6 min. There were no significant differences between the 12 h EVP and 24 h EVP groups at perfusion end for the following parameters: MAP (p = 0.63), pH (p = 0.77), pO2 (p = 0.20), venous pCO
conclusionEVP preserved flaps for 24 h within physiologic parameters and without development of edema. EVP may extend preservation time for VCAs.
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