ArticleJournal of biochemical and molecular toxicology2025
Synthesis and Investigation of Antibacterial Properties of Thymol, Carvacrol, Eugenol, and Perillyl Alcohol Based β-Halo Alcohol and β-Halo Thiol Compounds.
Article in Journal of biochemical and molecular toxicology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Polymer-Based Scaffolds Incorporating Selected Essential Oil Components for Wound Healing: A Review.Pharmaceutics · 2025Review
Corrections and comments
- Erratum issued
Authors and funding
5 authors.
Funding
Abstract
A total of 12 new β-halo alcohols and 12 new β-halo thiol derivatives were synthesized. Natural alcohol compounds with known pharmacological properties were selected as starting substrates, aiming to synthesize compounds that have the potential to exhibit biological activity. The synthesis of β-halo alcohol derivatives involved a two-step process, while β-halo thiol derivatives were carried out in three steps. Effective and inexpensive methods were used for all transformations. Yields for β-halo alcohol derivatives ranged from 79% to 82%, and for β-halo thiol derivatives from 66% to 71%. Their antibacterial properties against some gram (+) (Staphylococcus aureus, Enterococcus faecalis) and gram (-) (Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa) strains were investigated. The antibacterial effects of 24 newly synthesized compounds were compared to commercially available antibiotics Chloramphenicol and Streptomycin.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.