Evidence map›Paper›PMID 39959893›Full record

ArticleNeurosurgery practice2024

Does an Unintended Durotomy in Metastatic Spine Surgery Lead to Shorter Survival?

Lakshmi Suryateja Gangavarapu, Hani Chanbour, Gabriel A Bendfeldt, Iyan Younus, Soren Jonzzon, Silky Chotai, Amir M Abtahi, Byron F Stephens, Scott L Zuckerman

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Article in Neurosurgery practice, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Lakshmi Suryateja GangavarapuVanderbilt University School of Medicine, Nashville, Tennessee, USA.
Hani ChanbourDepartment of Neurological Surgery, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Gabriel A BendfeldtVanderbilt University School of Medicine, Nashville, Tennessee, USA.
Iyan YounusDepartment of Neurological Surgery, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Soren JonzzonDepartment of Neurological Surgery, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Silky ChotaiDepartment of Neurological Surgery, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Amir M AbtahiDepartment of Neurological Surgery, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Byron F StephensDepartment of Neurological Surgery, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Scott L ZuckermanDepartment of Neurological Surgery, Vanderbilt University Medical Center, Nashville, Tennessee, USA.ORCID https://orcid.org/0000-0003-2951-2942

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

objectivesWhether unintended durotomy in metastatic spine surgery seeds tumor in the central nervous system (CNS) remains unknown. Our objectives were to (1) determine the rate of unintended durotomy, (2) identify the preoperative and perioperative factors that increase the risk of unintended durotomy, and (3) determine whether unintended durotomy affected local recurrence (LR), any spinal recurrence, and overall survival.

methodsA single-center, retrospective cohort study of patients undergoing metastatic spine surgery between January 2010 to January 2021 was undertaken. The primary exposure variable was the occurrence of unintended durotomy. Multivariable logistic/linear regression were performed controlling for age, body mass index, tumor size, other organ metastases, and preoperative radiotherapy/chemotherapy.

resultsOf 354 patients undergoing surgery for extradural spinal metastasis, 19 patients (5.4%) had an unintended durotomy. Preoperatively: No difference was found between patients with and without unintended durotomy regarding basic demographics, comorbidities (

conclusionIn patients undergoing surgery for extradural spinal metastases, 5% had an unintended durotomy, and costotransversectomies were associated with increased risk of an unintended durotomy. Unintended durotomies did not lead to increased LR or shorter survival. Taken together, shortened survival due to seeding tumor into the CNS after an unintended durotomy was not observed.

Indexed as

CNS spreadCSF leakExtraduralRecurrenceSpine metastasisSurvival

Identifiers

PMID39959893
PMCPMC11783639

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