ArticleFrontiers in physiology2024
Rat perivascular adipose tissue microvasculature revealed by tissue clearing.
Article in Frontiers in physiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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1 citing paper in PubMed.
- Single-nucleus analysis of thoracic perivascular adipose tissue reveals critical changes in cell composition, communication, and gene regulatory networks induced by a high fat hypertensive diet.bioRxiv : the preprint server for biology · 2025Article
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4 authors.
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Abstract
Perivascular adipose tissue (PVAT) surrounds the majority of blood vessels and plays diverse roles in vascular and metabolic functions. The hormonal and lipid exchange functions of PVAT require access to blood vessels. However, the microvascular supply of PVAT, especially in rats, remains enigmatic due to technical restraints involved in imaging fat depots. Therefore, we developed and validated an approach to visualize the microvasculature of PVAT in rats. In this study, we report a stepwise protocol as a method to clear and visualize the microvasculature of the thoracic aortic PVAT in the Dahl salt-sensitive (SS) rat. Blood vessels are first traced in anesthetized rats using
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