Evidence map›Paper›PMID 39959793›Full record

ReviewTanaffos2024

Safety and Adverse Effects Related to COVID-19 Viral Vector Vaccines: A Systematic Review.

SeyedAhmad SeyedAlinaghi, Ava Pashaei, Marcarious M Tantuoyir, Amirali Karimi, Hengameh Mojdeganlou, Newsha Nazarian, Farzin Vahedi, Arian Afzalian, Parnian Shobeiri, Mohsen Dashti and 4 more

Abstract readReview
PubMed Full text at PMC
In one paragraph

Review in Tanaffos, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

SeyedAhmad SeyedAlinaghiIranian Research Center for HIV/AIDS, Iranian Institute for Reduction of High Risk Behaviors, Tehran University of Medical Sciences, Tehran, Iran.
Ava PashaeiSchool of Nursing, The British Columbia University, Vancouver, British Columbia, Canada.
Marcarious M TantuoyirSchool of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Amirali KarimiSchool of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Hengameh MojdeganlouDepartment of Pathology, The Johns Hopkins University, School of Medicine, Baltimore, MD, USA.
Newsha NazarianSchool of Medicine, Islamic Azad University, Tehran, Iran.
Farzin VahediSchool of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Arian AfzalianSchool of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Parnian ShobeiriSchool of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Mohsen DashtiDepartment of Radiology, Tabriz University of Medical Sciences, Tabriz, Iran.
Afsaneh GhasemzadehDepartment of Radiology, Tabriz University of Medical Sciences, Tabriz, Iran.
Pegah MirzapourIranian Research Center for HIV/AIDS, Iranian Institute for Reduction of High Risk Behaviors, Tehran University of Medical Sciences, Tehran, Iran.
Sahar Nooralioghli ParikhaniSchool of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Esmaeil MehraeenDepartment of Health Information Technology, Khalkhal University of Medical Sciences, Khalkhal, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: There have been safety concerns regarding the COVID-19 vaccines because of their unprecedented speed of development. Therefore, systematic reviews are necessary to address these concerns and reduce public hesitancy regarding COVID-19 vaccines. This study aims to systematically review the reported adverse events related to viral vector COVID-19 vaccines. Materials and Methods: We performed a systematic search in the databases of PubMed, Scopus, Web of Science, and Cochrane on September 15 Results: The adenovirus vector-based COVID-19 vaccines, including the Janssen COVID-19 vaccine, the AstraZeneca COVID-19 vaccine, and the Sputnik V vaccine were included in this review. Among these vaccines, the AstraZeneca has presented enormous side effects with most being systemic and a few sporadic cases of life-threatening events such as thrombosis and capillary leak syndrome and even death in a few cases. Prominent systemic side effects of the adenovirus vaccines include fever, fatigue, malaise, arthralgia, myalgia, sweating, and dizziness. Erythema, swelling, tenderness, itching, and numbness at the injection site are the most common local reactions. Conclusion: It appeared that the frequency of serious adverse events is negligible, and vaccination to prevent severe COVID-19 and mortality has greater benefits than adverse events in the general population.

Indexed as

Adenovirus vectorAdverse effectsAdverse eventsCOVID-19COVID-19 VaccinesSARS-CoV-2

Identifiers

PMID39959793
PMCPMC11825072

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.