ArticleNutrition research and practice2025
Association of dietary intake of total fat and fatty acids with the Omega-3 Index: a cross-sectional analysis of NHANES 2011-2012.
Article in Nutrition research and practice, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
BACKGROUND/
objectivesThe Omega-3 Index (O3I), which is the total eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) in erythrocytes as a percentage of total fatty acids (FAs), is associated with fish intake. O3I also varies with body mass index, age, sex, and dietary factors other than the intake of n-3 polyunsaturated fatty acids (PUFAs). This study examined the relationship between the dietary intake of total fat and FA classes, and O3I, specifically regarding EPA+DHA intake. SUBJECTS/
methodsData on dietary intake and serum FAs from 2,370 participants (1,192 males and 1,178 females) aged 18-79 yrs, collected during the 2011-2012 National Health and Nutrition Examination Survey, were used in this study. The O3I was estimated from the serum EPA+DHA content.
resultsIn the total population, O3I showed an inverse correlation with the intake of total fat (r = -0.417), saturated FAs (SFAs; r = -0.423), and monounsaturated fatty acids (MUFAs; r = -0.412) (
conclusionThe intakes of total fat, SFA, and MUFA negatively influenced O3I, independent of n-3 PUFA intake.
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