Evidence map›Paper›PMID 39959711›Full record

ArticlePNAS nexus2025

The endoplasmic reticulum luminal Ca

Elisa Bovo, Roman Nikolaienko, Daniel Kahn, L Michel Espinoza-Fonseca, Aleksey V Zima

Abstract read
In one paragraph

Article in PNAS nexus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Elisa BovoDepartment of Cell and Molecular Physiology, Stritch School of Medicine, Loyola University Chicago, Maywood, IL 60153, USA.ORCID https://orcid.org/0000-0002-9709-6381
Roman NikolaienkoDepartment of Cell and Molecular Physiology, Stritch School of Medicine, Loyola University Chicago, Maywood, IL 60153, USA.ORCID https://orcid.org/0000-0002-9836-2880
Daniel KahnDepartment of Cell and Molecular Physiology, Stritch School of Medicine, Loyola University Chicago, Maywood, IL 60153, USA.
L Michel Espinoza-FonsecaDivision of Cardiovascular Medicine, Department of Internal Medicine, Center for Arrhythmia Research, University of Michigan, Ann Arbor, MI 48109, USA.ORCID https://orcid.org/0009-0007-1006-6504
Aleksey V ZimaDepartment of Cell and Molecular Physiology, Stritch School of Medicine, Loyola University Chicago, Maywood, IL 60153, USA.ORCID https://orcid.org/0000-0001-7280-2924

Funding

Structural Dynamics of Cardiac Muscle Calcium ATPase RegulationR01HL139065 · NHLBI · UNIVERSITY OF MINNESOTA · PI Robyn T Rebbeck, David D Thomas · 2020 to 2026
$5.2M
Hit-to-lead optimization for heart failure drug discoveryR01HL148068 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI ESPINOZA-FONSECA, LENNANE MICHEL, HERRON, TODD JOSEPH · 2019 to 2022
$2.9M
Molecular mechanisms and regulation of the calcium pump in the heartR01GM120142 · NIGMS · UNIVERSITY OF MINNESOTA · PI ESPINOZA-FONSECA, LENNANE MICHEL · 2016 to 2020
$1.7M
Calcium release channel dysfunction: molecular mechanismsR01HL130231 · NHLBI · LOYOLA UNIVERSITY CHICAGO · PI ZIMA, ALEKSEY V · 2016 to 2019
$1.5M
NHLBI NIH HHS R01 HL130231NHLBI NIH HHS R01 HL139065NHLBI NIH HHS R01 HL148068NIGMS NIH HHS R01 GM120142
6 · The paper itself

Abstract

The type 2a sarcoplasmic/endoplasmic reticulum Ca

Indexed as

calcium ATPasecalcium pumpendoplasmic reticulumfluorescent microscopyintracellular calcium signaling

Identifiers

PMID39959711
PMCPMC11826342

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.