Evidence map›Paper›PMID 39959336›Full record

ArticleActa clinica Croatica2024

SERUM ACTIVITY OF ANTIOXIDATIVE ENZYMES AND CONCENTRATION OF MALONDIALDEHYDE AS PREDICTORS OF COLORECTAL CANCER STAGE IN CROATIAN PATIENTS.

Ana Mojsović Ćuić, Lana Feher Turković, Sandra Domjanić Drozdek, Ivan Jurak, Domagoj Đikić, Irena Landeka Jurčević, Marija Skoko, Nina Rotim, Danko Velimir Vrdoljak, Nikola Đaković

Abstract read
In one paragraph

Article in Acta clinica Croatica, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Ana Mojsović ĆuićUniversity of Applied Health Sciences, Zagreb, Croatia.
Lana Feher TurkovićUniversity of Applied Health Sciences, Zagreb, Croatia.
Sandra Domjanić DrozdekUniversity of Applied Health Sciences, Zagreb, Croatia.
Ivan JurakUniversity of Applied Health Sciences, Zagreb, Croatia.
Domagoj ĐikićDivision of Animal Physiology, Faculty of Science, University of Zagreb, Zagreb, Croatia.
Irena Landeka JurčevićLaboratory of Chemistry and Food Biochemistry, Faculty of Food Technology and Biotechnology, University of Zagreb, Zagreb, Croatia.
Marija SkokoUniversity Hospital for Tumors, Sestre milosrdnice University Hospital Center, Zagreb, Croatia.
Nina Rotimstudent, School of Medicine, University of Zagreb, Zagreb, Croatia.
Danko Velimir VrdoljakUniversity Hospital for Tumors, Sestre milosrdnice University Hospital Center, Zagreb, Croatia.
Nikola ĐakovićInstitute for Clinical Medical Research and Teaching, Sestre milosrdnice University Hospital Center, Zagreb, Croatia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

One of the factors involved in the colorectal cancer development is intracellular oxidative stress and antioxidative imbalance. The study aimed to explore the link between oxidative stress measured by the activity of antioxidative markers and lipid peroxidation product malondialdehyde (MDA) as possible cancer predictors of colorectal cancer by using several statistical methods. The study included 50 adult colorectal cancer patients of both genders. MDA level, the activity of antioxidative markers superoxide dismutase and catalase, and glutathione concentration were determined in patient sera. There was no age difference between male and female patients (p=0.579), and no gender differences according to cancer site (p=0.995), stage (p=0.083), and size (p=0.245). There were no differences in the levels of studied enzymes. Correlation analysis of antioxidative markers and MDA with cancer size and patient age revealed strongest individual correlation between the MDA and cancer size variables (r=-0.56).

Indexed as

CatalaseColorectal NeoplasmsMalondialdehydeSuperoxide DismutaseAdultAgedAntioxidantsBiomarkers, TumorCroatiaFemaleGlutathioneHumansMaleMiddle AgedNeoplasm StagingOxidative StressAntioxidantsBiomarkers, TumorCatalaseGlutathioneMalondialdehydeSuperoxide DismutaseAntioxidative markersColorectal cancerMalondialdehydeOxidative stress

Identifiers

PMID39959336
PMCPMC11827401

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.